Evidence map›Paper›PMID 33666110›Full record

ReviewThe neuroradiology journal2021

Multiparametric magnetic resonance imaging and positron emission tomography findings in neurodegenerative diseases: Current status and future directions.

Neetu Soni, Manish Ora, Girish Bathla, Chandana Nagaraj, Laura L Boles Ponto, Michael M Graham, Jitender Saini, Yusuf Menda

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06682624 (Magnetic Resonance Imaging Pattern Recognition Approach in Pediatric Inherited Neurodegenerative Diseases), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06682624 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Magnetic Resonance Imaging Pattern Recognition Approach in Pediatric Inherited Neurodegenerative Diseases

Typeobservational_patient_registrySponsorSohag UniversityRan2025 to 2026Enrolled40ConditionsPediatric Neurological DisorderArmsMRI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Neetu SoniUniversity of Iowa Hospitals and Clinics, USA.ORCID https://orcid.org/0000-0003-2082-1634
Manish OraDepartment of Nuclear Medicine, SGPGIMS, India.
Girish BathlaNeuroradiology Department, University of Iowa Hospitals and Clinics, USA.
Chandana NagarajDepartment of Neuro Imaging and Interventional Radiology, NIMHANS, India.
Laura L Boles PontoPET Imaging Center, University of Iowa Hospitals and Clinics, USA.ORCID https://orcid.org/0000-0003-1197-6714
Michael M GrahamDivision of Nuclear Medicine, University of Iowa Hospitals and Clinics, USA.
Jitender SainiDepartment of Neuro Imaging and Interventional Radiology, NIMHANS, India.
Yusuf MendaUniversity of Iowa Hospitals and Clinics, USA.
University of Iowa Hospitals and Clinics · USNational Institute of Mental Health and Neurosciences · INSanjay Gandhi Post Graduate Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases (NDDs) are characterized by progressive neuronal loss, leading to dementia and movement disorders. NDDs broadly include Alzheimer's disease, frontotemporal lobar degeneration, parkinsonian syndromes, and prion diseases. There is an ever-increasing prevalence of mild cognitive impairment and dementia, with an accompanying immense economic impact, prompting efforts aimed at early identification and effective interventions. Neuroimaging is an essential tool for the early diagnosis of NDDs in both clinical and research settings. Structural, functional, and metabolic imaging modalities, including magnetic resonance imaging (MRI) and positron emission tomography (PET), are widely available. They show encouraging results for diagnosis, monitoring, and treatment response evaluation. The current review focuses on the complementary role of various imaging modalities in relation to NDDs, the qualitative and quantitative utility of newer MRI techniques, novel radiopharmaceuticals, and integrated PET/MRI in the setting of NDDs.

Indexed as

Multiparametric Magnetic Resonance ImagingNeurodegenerative DiseasesHumansMagnetic Resonance ImagingNeuroimagingPositron-Emission TomographyAlzheimer’s diseasedementiafrontotemporal dementiaMRINeurodegenerative diseaseparkinsonian syndromesPETprimary progressive aphasia

Identifiers

PMID33666110
PMCPMC8447818
OpenAlexW3134348426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.