ArticleInfectious Disease Modelling2021
SCHISTOX: An individual based model for the epidemiology and control of schistosomiasis.
Article in Infectious Disease Modelling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Associations of water contact frequency, duration, and activities with schistosome infection risk: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2023Pooled it
- How important is the spatial movement of people in attempts to eliminate the transmission of human helminth infections by mass drug administration?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Trial
- Schistosomiasis japonica transmission dynamics: mathematical modeling in guiding One Health approach control strategies.Infectious diseases of poverty · 2026Article
- Predicting schistosome transmission in rural Uganda using water contact data from wearable GPS devices.Nature health · 2026Article
- Development of a dynamical model to enhance understanding of epidemiology of schistosomiasis in school-aged-children.Scientific reports · 2025Article
- Population-level impact of mass drug administration against schistosomiasis with anthelmintic drugs targeting juvenile schistosomes: a modelling study.The Lancet. Microbe · 2025Article
- How improvements to drug effectiveness impact mass drug administration for control and elimination of schistosomiasis.PLoS neglected tropical diseases · 2025Article
- Current water contact and Schistosoma mansoni infection have distinct determinants: a data-driven population-based study in rural Uganda.Nature communications · 2024Article
- Revisiting the impact of Schistosoma mansoni regulating mechanisms on transmission dynamics using SchiSTOP, a novel modelling framework.PLoS neglected tropical diseases · 2024Article
- How Does Treatment Coverage and Proportion Never Treated Influence the Success of Schistosoma mansoni Elimination as a Public Health Problem by 2030?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Modeling the persistence of Opisthorchis viverrini worm burden after mass-drug administration and education campaigns with systematic adherence.PLoS neglected tropical diseases · 2024Article
- Modelling morbidity for neglected tropical diseases: the long and winding road from cumulative exposure to long-term pathology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- A Critical Review on Human Malaria and Schistosomiasis Vaccines: Current State, Recent Advancements, and Developments.Vaccines · 2023Review
- Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases: a modelling study.The Lancet. Global health · 2022Article
- Determining the optimal strategies to achieve elimination of transmission for Schistosoma mansoni.Parasites & vectors · 2022Article
- Shifting the dynamics: implementation of locally driven, mixed-methods modelling to inform schistosomiasis control and elimination activities.BMJ global health · 2022Article
- Maintaining Low Prevalence of Schistosoma mansoni: Modeling the Effect of Less Frequent Treatment.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A stochastic individual based model, SCHISTOX, has been developed for the study of schistosome transmission dynamics and the impact of control by mass drug administration. More novel aspects that can be investigated include individual level adherence and access to treatment, multiple communities, human sex population dynamics, and implementation of a potential vaccine. Many of the model parameters have been estimated within previous studies and have been shown to vary between communities, such as the age-specific contact rates governing the age profiles of infection. However, uncertainty remains as there are wide ranges for certain parameter values and a few remain relatively unknown. We analyse the model dynamics by parameterizing it with published parameter values. We also discuss the development of SCHISTOX in the form of a publicly available open-source GitHub repository. The next key development stage involves validating the model by calibrating to epidemiological data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.