ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2021
Body weight changes and longitudinal associations with cognitive decline among community-dwelling older adults.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Body weight and BMI variability linked to dementia risk: A meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- Association of a novel nutritional index, the triglyceride-cholesterol-body weight index (TCBI), with incident mild cognitive impairment: CHARLS 2011-2018.Frontiers in nutrition · 2026Article
- Variability in body weight and body composition and cognitive trajectories in older adults in the United States.Obesity (Silver Spring, Md.) · 2025Article
- Socioeconomic Status and Associations with Nutrition in Icelandic Community-Dwelling Older Adults: Results from the AGES-Reykjavik Study.Nutrients · 2025Article
- Trajectories of general and central obesity beyond middle age in relation to late-life cognitive decline and dementia.Obesity (Silver Spring, Md.) · 2025Article
- Article
- Association of changes in predicted body composition with subsequent risk of dementia.Annals of clinical and translational neurology · 2024Article
- Association Between Late-Life Weight Change and Dementia: A Population-based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Body weight changes and longitudinal associations with cognitive decline among community-dwelling older adults.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
- Body mass index, weight change in midlife, and dementia incidence: the Japan Public Health Center-based Prospective Study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
10 authors.
Funding
Abstract
introductionWe aim to investigate the longitudinal associations between changes in body weight (BW) and declines in cognitive function and risk of mild cognitive impairment (MCI)/dementia among cognitively normal individuals 65 years or older.
methodsData from the Age Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik Study) including 2620 participants, were examined using multiple logistic regression models. Cognitive function included speed of processing (SP), executive function (EF), and memory function (MF). Changes in BW were classified as; weight loss (WL), weight gain (WG), and stable weight (SW).
resultsMean follow-up time was 5.2 years and 61.3% were stable weight. Participants who experienced WL (13.4%) were significantly more likely to have declines in MF and SP compared to the SW group. Weight changes were not associated with EF. WL was associated with a higher risk of MCI, while WG (25.3%) was associated with a higher dementia risk, when compared to SW. DISCUSSION: Significant BW changes in older adulthood may indicate impending changes in cognitive function.
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