Evidence map›Paper›PMID 33665264›Full record

ArticleData in brief2021

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.

Madhulika Sharma, Sireesha Yerrathota, Mackenzie M Thornton, Sumedha Gunewardena

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Madhulika SharmaDepartments of Internal Medicine, United States.
Sireesha YerrathotaDepartments of Internal Medicine, United States.
Mackenzie M ThorntonDepartments of Internal Medicine, United States.
Sumedha GunewardenaMolecular and integrative physiology, United States.
University of Kansas Medical Center · USFlorida College of Integrative Medicine · US

Funding

Using PCORnet to Expand the DS-CONNECT Cohort Through Healthcare System Recruitment, Incorporating Electronic Health Records, and Assessing Self-DeterminationU54HD090216 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI COLOMBO, JOHN A. · 2016 to 2020
$6.2M
Implications of Notch signaling in HIV associated nephropathyR01DK108433 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SHARMA, MADHULIKA · 2015 to 2019
$743k
NICHD NIH HHS U54 HD090216NIDDK NIH HHS R01 DK108433
6 · The paper itself

Abstract

The Notch signaling pathway is an important conserved pathway for normal homeostasis during development. However, targeted deletion of Notch4 (

Indexed as

Chronic kidney diseaseHIVANInflammationTg26

Identifiers

PMID33665264
PMCPMC7905437
OpenAlexW3129372324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.