ReviewFrontiers in cardiovascular medicine2021
Right Ventricular Damage in COVID-19: Association Between Myocardial Injury and COVID-19.
Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Association between right ventricular dysfunction and mortality in COVID-19 patients: A systematic review and meta-analysis.Clinical cardiology · 2021Pooled it
- Revisiting the monocrotaline-treated rat as a model of inflammatory lung disease: COVID-19 and future pandemic threats?Animal models and experimental medicine · 2025Review
- Respiratory Syncytial Virus (RSV)-Related Hospitalization and Increased Rate of Cardiovascular Events in Older Adults.Journal of the American Geriatrics Society · 2025Article
- MRI of cardiac involvement in COVID-19.The British journal of radiology · 2024Review
- Role of Imaging in Diagnosis and Management of COVID-19: Evidence-Based Approaches.Advances in experimental medicine and biology · 2024Review
- Pulmonary hypertension predicts higher mortality in patients admitted with severe COVID-19 infection.SAGE open medicine · 2023Article
- Diagnosis and treatment of right ventricular dysfunction in patients with COVID-19 on veno-venous extra-corporeal membrane oxygenation.Journal of cardiothoracic surgery · 2022Article
- Role of cardiovascular magnetic resonance imaging in COVID-19 recovered patients: A short-term follow-up study.Echocardiography (Mount Kisco, N.Y.) · 2022Article
- Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019 (COVID-19).Journal of intensive medicine · 2022Article
- Myocardial function in COVID-19 patients after hospital discharge: a descriptive study comparing the first and second 'wave' patients.The international journal of cardiovascular imaging · 2022Article
- Right Ventricular Failure Manifesting in Corona Virus Disease 2019 Acute Respiratory Distress Syndrome: A Call to Transition from Venovenous Extracorporeal Membranous Oxygenation to Right Ventricular Assist Device Extracorporeal Membranous Oxygenation.Journal of cardiothoracic and vascular anesthesia · 2022Article
- The cross-talk of lung and heart complications in COVID-19: Endothelial cells dysfunction, thrombosis, and treatment.Frontiers in cardiovascular medicine · 2022Review
- Assessment of Right Ventricular Mechanics by 3D Transesophageal Echocardiography in the Early Phase of Acute Respiratory Distress Syndrome.Frontiers in cardiovascular medicine · 2022Article
- Right ventricle early inflow-outflow index may inform about the severity of pneumonia in patients with COVID-19.Journal of clinical ultrasound : JCU · 2022Article
- Continuous long-term wireless measurement of right ventricular pressures and estimated diastolic pulmonary artery pressure in patients with severe COVID-19 acute respiratory distress syndrome.ESC heart failure · 2021Article
- TEGJournal of clinical medicine · 2021Review
- Lung Cancer and Heart Disease Risks Associated With Low-Dose Pulmonary Radiotherapy to COVID-19 Patients With Different Background Risks.International journal of radiation oncology, biology, physics · 2021Article
- Role of Imaging in Diagnosis and Management of COVID-19: A Multiorgan Multimodality Imaging Review.Frontiers in medicine · 2021Review
- Letter to the Editor: Influence of right ventricular structure and function on hospital outcomes in COVID-19 patients.Heart & lung : the journal of critical careArticle
- Influence of right ventricular structure and function on hospital outcomes in COVID-19 patients.Heart & lung : the journal of critical careArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, is a global pandemic. It has resulted in considerable morbidity and mortality around the world. The respiratory system is the main system invaded by the virus involved in COVID-19. In addition to typical respiratory manifestations, a certain proportion of severe COVID-19 cases present with evidence of myocardial injury, which is associated with excessive mortality. With availability of an increasing amount of imaging data, right ventricular (RV) damage is prevalent in patients with COVID-19 and myocardial injury, while left ventricular damage is relatively rare and lacks specificity. The mechanisms of RV damage may be due to increased RV afterload and decreased RV contractility caused by various factors, such as acute respiratory distress syndrome, pulmonary thrombosis, direct viral injury, hypoxia, inflammatory response and autoimmune injury. RV dysfunction usually indicates a poor clinical outcome in patients with COVID-19. Timely and effective treatment is of vital importance to save patients' lives as well as improve prognosis. By use of echocardiography or cardiovascular magnetic resonance, doctors can find RV dilatation and dysfunction early. By illustrating the phenomenon of RV damage and its potential pathophysiological mechanisms, we will guide doctors to give timely medical treatments (e.g., anticoagulants, diuretics, cardiotonic), and device-assisted therapy (e.g., mechanical ventilation, extracorporeal membrane oxygenation) when necessary for these patients. In the paper, we examined the latest relevant studies to investigate the imaging features, potential mechanisms, and treatments of myocardial damage caused by COVID-19. RV damage may be an association between myocardial damage and lung injury in COVID-19. Early assessment of RV geometry and function will be helpful in aetiological determination and adjustment of treatment options.
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