ArticleThe World Allergy Organization journal2021
The Peanut Allergy Burden Study: Impact on the quality of life of patients and caregivers.
Article in The World Allergy Organization journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Guideline
- Quality Appraisal of Quality of Life Research in Children and Adolescents with Food Allergy: A Systematic Review.International archives of allergy and immunology · 2024Pooled it
- Trial
- Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy.Allergy · 2025Trial
- Efficacy and Safety of Dupilumab in Children With Peanut Allergy: A Multicenter, Open-Label, Phase II Study.Allergy · 2025Trial
- Desensitization and remission after peanut sublingual immunotherapy in 1- to 4-year-old peanut-allergic children: A randomized, placebo-controlled trial.The Journal of allergy and clinical immunology · 2024Trial
- Peanut oral immunotherapy at a single academic medical center using a volume-based approach with store-purchased peanut products.The journal of allergy and clinical immunology. Global · 2026Article
- "It's a Permanent Struggle to Manage It Really": Psychological Burden and Coping Strategies of Adults Living With Food Allergy.Qualitative health research · 2026Article
- Regional Profile of Food Allergen Sensitization Among Children in Southwest China: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Public Information Needs and Interest in Specific Food and Drug Allergy Disorders in Germany (2022-2024): Google Search Engine Analysis.JMIR formative research · 2025Article
- Decoding Early Clues: Immune Mechanisms, Prevention, Diagnosis, and Treatment of IgE-Mediated Peanut and Tree Nut Allergy in Children.Biomedicines · 2025Review
- Generic Health-Related Quality of Life of Children With Severe Peanut or Tree Nut Allergy.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Review
- Community and academic allergists' perspectives on integrating biologics into food allergy care: A qualitative study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Article
- Review
- Characterization and Incidence of Sunflower Seed Allergy in a Pediatric Allergy Clinic.The journal of allergy and clinical immunology. In practice · 2024Article
- Epinephrine availability and allergen avoidance behaviors among caregivers of young children with food allergy.Journal of food allergy · 2024Article
- The Future of Food Allergy Management: Advancements in Therapies.Current allergy and asthma reports · 2024Review
- Post hoc analysis examining symptom severity reduction and symptom absence during food challenges in individuals who underwent oral immunotherapy for peanut allergy: results from three trials.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Food allergy knowledge, attitudes and beliefs of kindergarten teachers in Kuwait: a cross-sectional study.BMJ paediatrics open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeanut allergy (PA) places significant burden on peanut-allergic individuals and their families, yet limited research in the United States has quantitatively examined the impact on peanut-allergic individuals and their families' health-related quality of life (HRQoL). The Peanut Allergy Burden Study (PABS) aimed to quantify the impact of PA on the general and disease-specific HRQoL of children, adolescents, and adults with PA, as well as caregivers of children with PA.
methodsA cross-sectional survey design was employed to examine the real-world impact of PA in children, adolescents, and adults with PA, and caregivers of children with PA.
resultsOf 153 adult patients, 102 adolescents, and 382 caregivers of peanut-allergic children (n = 382), 6.8% and 24.8% of participants indicated being dissatisfied or somewhat dissatisfied, respectively, with current approaches to avoid or prevent PA reactions. Approximately two-thirds of patients and caregivers indicated that PA interferes at least somewhat with daily living. In terms of general HRQoL, adolescents, adult patients, and caregivers indicated that mental/psychosocial health was more problematic than physical health. PA patients and caregivers indicated worse HRQoL in all domains compared to healthy samples, and worse overall HRQoL, psychosocial, emotional, and social functioning than a sample of chronically ill patients. Results from the allergy-specific HRQoL measures showed that adolescents experienced greater impairment in overall HRQoL due to PA and in allergen avoidance and dietary restriction than adults.
conclusionPA negatively affects the general and PA-specific HRQoL of both patients and caregivers. The high emotional and psychosocial burden, in particular, demonstrates significant unmet need for patients with PA and their caregivers. Future work on treatment and preventive options to improve HRQoL for PA patients, particularly adolescents and their families, is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.