Evidence map›Paper›PMID 33664897›Full record

ArticleJournal of arrhythmia2021

Current status and role of programmed ventricular stimulation in patients without sustained ventricular arrhythmias and reduced ejection fraction: Analysis of the Japan cardiac device treatment registry database.

Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Kohei Ishibashi, Tomoyuki Kabutoya, Yasuhiro Yoshiga, Ritsuko Kohno, Haruhiko Abe, Akihiko Nogami, Members of the Implantable Cardioverter‐Defibrillator (ICD) Committee of the Japanese Heart Rhythm Society

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Hisashi YokoshikiDepartment of Cardiovascular Medicine Sapporo City General Hospital Sapporo Japan.ORCID https://orcid.org/0000-0002-6247-2148
Akihiko ShimizuUBE Kohsan Central Hospital Upe Japan.
Takeshi MitsuhashiDepartment of Cardiovascular Medicine Hoshi General Hospital Koriyama Japan.
Kohei IshibashiDepartment of Cardiovascular Medicine National Cerebral and Cardiovascular Center Suita Japan.
Tomoyuki KabutoyaDivision of Cardiovascular Medicine Department of Medicine Jichi Medical University School of Medicine Shimotsuke Japan.
Yasuhiro YoshigaDivision of Cardiology Department of Medicine and Clinical Science Yamaguchi University Graduate School of Medicine Ube Japan.
Ritsuko KohnoDepartment of Heart Rhythm Management University of Occupational & Environmental Health Kitakyushu Japan.
Haruhiko AbeDepartment of Heart Rhythm Management University of Occupational & Environmental Health Kitakyushu Japan.
Akihiko NogamiCardiovascular Division Faculty of Medicine University of Tsukuba Tsukuba Japan.
Members of the Implantable Cardioverter‐Defibrillator (ICD) Committee of the Japanese Heart Rhythm Society
University of Occupational and Environmental Health Japan · JPCentral Glass (Japan) · JPJichi Medical University · JPNational Cerebral and Cardiovascular Center · JPSapporo City General Hospital · JPStar General Hospital · JPUniversity of Tsukuba · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to clarify the current status and role of programmed ventricular stimulation in patients without sustained ventricular arrhythmias and reduced left ventricular ejection fraction (LVEF).

methodsThe follow-up data of the Japan cardiac device treatment registry (JCDTR) was analyzed in 746 patients with LVEF ≦35% and no prior history of sustained ventricular arrhythmias who underwent de novo implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy with a defibrillator (CRT-D) implantation between January 2011 and August 2015.

resultsElectrophysiological study (EPS) with programmed ventricular stimulation had been performed before the device implant in 118 patients (15.8%, EPS group). During the mean follow-up of 21 ± 12 months, the rate of freedom from any death and appropriate defibrillator therapy was not significantly different between EPS group (n = 118) and No EPS group (n = 628). NYHA class II-IV, and QRS duration were negatively associated with performing EPS. Among patients in the EPS group, the rate of ventricular tachycardia (VT)/ventricular fibrillation (VF) induction was 48%. The inducibility was not a predictor of appropriate defibrillator therapy, whereas BNP ≧535 pg/mL and no use of amiodarone were significantly associated with a risk of the appropriate therapy.

conclusionEPS for induction of VT/VF had been performed in about 16% of patients with reduced LVEF before primary prevention ICD/CRT-D implantation. Elevated BNP levels and no use of amiodarone, but not inducibility of VT/VF, appeared to be associated with appropriate defibrillator therapy in these populations.

Indexed as

cardiac resynchronization therapy with a defibrillator (CRT‐D)electrophysiological study (EPS)implantable cardioverter‐defibrillator (ICD)primary preventionventricular fibrillation (VF)ventricular tachycardia (VT)

Identifiers

PMID33664897
PMCPMC7896472
OpenAlexW3107313764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.