Evidence map›Paper›PMID 33664847›Full record

ArticleTheranostics2021

Vitamin C sensitizes triple negative breast cancer to PI3K inhibition therapy.

Sushmita Mustafi, Vladimir Camarena, Rehana Qureshi, David W Sant, Zachary Wilkes, Daniel Bilbao, Joyce Slingerland, Susan B Kesmodel, Gaofeng Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sushmita MustafiJohn P. Hussman Institute for Human Genomics, Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida.
Vladimir CamarenaJohn P. Hussman Institute for Human Genomics, Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida.
Rehana QureshiSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.
David W SantJohn P. Hussman Institute for Human Genomics, Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida.
Zachary WilkesJohn P. Hussman Institute for Human Genomics, Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida.
Daniel BilbaoSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.
Joyce SlingerlandSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.
Susan B KesmodelSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida.
Gaofeng WangJohn P. Hussman Institute for Human Genomics, Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida.
University of Miami · USDr. John T. Macdonald Foundation · USSylvester Comprehensive Cancer Center · US

Funding

Epigenetic Prevention of Diabetic Neuropathy by Vitamin CR01NS089525 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WANG, GAOFENG · 2014 to 2017
$1.2M
NINDS NIH HHS R01 NS089525
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminopyridinesAnimalsApoptosisAscorbic AcidCell Line, TumorDrug SynergismFemaleGene Expression Regulation, NeoplasticHistone CodeHumansMiceMice, Inbred NODMice, SCIDMolecular Targeted TherapyMorpholinesPhosphoinositide-3 Kinase InhibitorsAminopyridinesAscorbic AcidMorpholinesNVP-BKM120Phosphoinositide-3 Kinase Inhibitors

Identifiers

PMID33664847
PMCPMC7914363
OpenAlexW3126874260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.