Evidence map›Paper›PMID 33664805›Full record

ArticleOncology letters2021

IL10 hypomethylation is associated with the risk of gastric cancer.

Junjian Tang, Ranran Pan, Lele Xu, Qinghua Ma, Xiuru Ying, Jun Zhao, Haibin Zhao, Li Miao, Yue Xu, Shiwei Duan and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Junjian TangDepartment of Vascular Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214000, P.R. China.
Ranran PanMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Lele XuDepartment of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215200, P.R. China.
Qinghua MaDepartment of Preventive Health, The Third People's Hospital of Xiangcheng District, Suzhou, Jiangsu 215134, P.R. China.
Xiuru YingMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Jun ZhaoMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Haibin ZhaoDepartment of Pathology, Taihu Hospital, Wuxi, Jiangsu 214004, P.R. China.
Li MiaoDepartment of Pediatrics, Xuzhou Medical University Affiliated Hospital of Lianyungang, Xuzhou, Jiangsu 222002, P.R. China.
Yue XuDepartment of Cell Biology, School of Medicine, Soochow University, Suzhou, Jiangsu 215007, P.R. China.
Shiwei DuanMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Jinzhi WangDepartment of Cell Biology, School of Medicine, Soochow University, Suzhou, Jiangsu 215007, P.R. China.
Ningbo University · CNSoochow University · CNLianyungang Oriental Hospital · CNWuxi Fourth People's Hospital · CNWuxi Taihu Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-10 (IL10), a pleiotropic cytokine secreted by type-2 helper (Th2) T cells, contributes to the oncogenic activation or inactivation of tumor-suppressor genes. The present study investigated whether hypomethylation of

Indexed as

CpG islandDNA methylationgastric cancerIL10quantitative methylation-specific PCR

Identifiers

PMID33664805
PMCPMC7882872
OpenAlexW3128381765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.