Evidence map›Paper›PMID 33664770›Full record

ArticleFrontiers in genetics2021

The Alteration of M6A-Tagged Transcript Profiles in the Retina of Rats After Traumatic Optic Neuropathy.

Xiaolin Qu, Kaixin Zhu, Zhenxing Li, Danfeng Zhang, Lijun Hou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiaolin QuDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Kaixin ZhuDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Zhenxing LiDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Danfeng ZhangDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Lijun HouDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai, China.
Second Military Medical University · CNNanjing General Hospital of Nanjing Military Command · CNShanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Messager RNA (mRNA) can be modified in a variety of ways, among which the modification of N6-methyladenosine (m6A) is one of the most common ones. Recent studies have found that the m6A modification in mRNA could functionally regulate the splicing, localization, translation, and stability of mRNA, which might be closely related to multiple diseases. However, the roles of m6A modification in traumatic optic neuropathy (TON) are unknown. Herein, we detected the expression of m6A-related genes

Indexed as

epigeneticsN6-methyladenosineoptic nerveretinatraumatic optic neuropathy

Identifiers

PMID33664770
PMCPMC7920991
OpenAlexW3132604283

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.