Evidence map›Paper›PMID 33664737›Full record

ReviewFrontiers in immunology2020

Anti-Pentraxin Antibodies in Autoimmune Diseases: Bystanders or Pathophysiological Actors?

Benoit Brilland, Emeline Vinatier, Jean-François Subra, Pascale Jeannin, Jean-François Augusto, Yves Delneste

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Insights into the Relationship between Pentraxin-3 and Cancer.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Benoit BrillandCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France.
Emeline VinatierUniversité d'Angers, INSERM, CRCINA, Angers, France.
Jean-François SubraCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France.
Pascale JeanninUniversité d'Angers, INSERM, CRCINA, Angers, France.
Jean-François AugustoCHU Angers, Service de Néphrologie-Dialyse-Transplantation, Angers, France.
Yves DelnesteUniversité d'Angers, INSERM, CRCINA, Angers, France.
Inserm · FRUniversité d'Angers · FRCentre Hospitalier Universitaire d'Angers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pentraxins are soluble innate immunity receptors involved in sensing danger molecules. They are classified as short (CRP, SAP) and long pentraxin subfamilies, including the prototypic long pentraxin PTX3. Pentraxins act mainly as bridging molecules favoring the clearance of microbes and dead cells. They are also involved in many other biological processes, such as regulation of complement activation, inflammation and tissue homeostasis. Autoantibodies directed against pentraxins have been reported in various autoimmune diseases, especially in systemic lupus erythematosus and ANCA-associated vasculitis. In this review, we review the main biological characteristics and functions of pentraxins and summarize data concerning autoantibodies directed against pentraxins in the context of autoimmune diseases and discuss their potential pathological role.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisAutoantibodiesBystander EffectC-Reactive ProteinHumansLupus Erythematosus, SystemicPentraxinsSerum Amyloid P-ComponentAutoantibodiesC-Reactive ProteinPentraxinsSerum Amyloid P-ComponentANCA-associated vasculitisanti-pentraxin autoantibodiesautoimmunitypentraxinssystemic lupus erythematosus

Identifiers

PMID33664737
PMCPMC7921723
OpenAlexW3133452333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.