Evidence map›Paper›PMID 33664430›Full record

ArticleCommunications biology2021

The posterior parietal cortex contributes to visuomotor processing for saccades in blindsight macaques.

Rikako Kato, Takuya Hayashi, Kayo Onoe, Masatoshi Yoshida, Hideo Tsukada, Hirotaka Onoe, Tadashi Isa, Takuro Ikeda

Abstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rikako KatoDepartment of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Japan.ORCID 0000-0003-3401-5713
Takuya HayashiLaboratory for Brain Connectomics Imaging, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID 0000-0001-7639-0197
Kayo OnoeLaboratory for Brain Connectomics Imaging, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Masatoshi YoshidaDepartment of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Japan.
Hideo TsukadaCentral Research Laboratory, Hamamatsu Photonics K.K., Hamamatsu, Japan.
Hirotaka OnoeCenter of Molecular Imaging Science, RIKEN, Kobe, Japan.
Tadashi IsaDepartment of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Japan. isa.tadashi.7u@kyoto-u.ac.jp.
Takuro IkedaDepartment of Developmental Physiology, National Institute for Physiological Sciences, Okazaki, Japan. taikeda-ns@umin.ac.jp.ORCID 0000-0003-1079-8725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with damage to the primary visual cortex (V1) lose visual awareness, yet retain the ability to perform visuomotor tasks, which is called "blindsight." To understand the neural mechanisms underlying this residual visuomotor function, we studied a non-human primate model of blindsight with a unilateral lesion of V1 using various oculomotor tasks. Functional brain imaging by positron emission tomography showed a significant change after V1 lesion in saccade-related visuomotor activity in the intraparietal sulcus area in the ipsi- and contralesional posterior parietal cortex. Single unit recordings in the lateral bank of the intraparietal sulcus (lbIPS) showed visual responses to targets in the contralateral visual field on both hemispheres. Injection of muscimol into the ipsi- or contralesional lbIPSs significantly impaired saccades to targets in the V1 lesion-affected visual field, differently from previous reports in intact animals. These results indicate that the bilateral lbIPSs contribute to visuomotor function in blindsight.

Indexed as

Behavior, AnimalSaccadesVision, OcularVisual PerceptionAnimalsBlindnessBrain MappingDisease Models, AnimalEvoked Potentials, VisualFemaleMacacaMalePositron-Emission TomographyVisual CortexVisual Fields

Identifiers

PMID33664430
PMCPMC7933420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.