Evidence map›Paper›PMID 33664406›Full record

ArticleScientific reports2021

Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons.

Rebecca Rani Das Gupta, Louis Scheurer, Pawel Pelczar, Hendrik Wildner, Hanns Ulrich Zeilhofer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Astrocyte Regulation of Spinal Circuit Function.Journal of neurochemistry · 2026
    Review
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  18. Excitatory and Inhibitory Neurons of the Spinal Cord Superficial Dorsal Horn Diverge in Their Somatosensory Responses and PlasticityThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rebecca Rani Das GuptaInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Louis ScheurerInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Pawel PelczarCenter for Transgenic Models, University of Basel, 4001, Basel, Switzerland.
Hendrik WildnerInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. hwildner@pharma.uzh.ch.
Hanns Ulrich ZeilhoferInstitute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. zeilhofer@pharma.uzh.ch.
ETH Zurich · CHUniversity of Zurich · CHUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spinal dorsal horn harbors a sophisticated and heterogeneous network of excitatory and inhibitory neurons that process peripheral signals encoding different sensory modalities. Although it has long been recognized that this network is crucial both for the separation and the integration of sensory signals of different modalities, a systematic unbiased approach to the use of specific neuromodulatory systems is still missing. Here, we have used the translating ribosome affinity purification (TRAP) technique to map the translatomes of excitatory glutamatergic (vGluT2

Indexed as

Protein BiosynthesisAnimalsgamma-Aminobutyric AcidGene Expression RegulationGlutamate DecarboxylaseGray MatterHumansMiceNeuropeptidesNeurotransmitter AgentsPosterior Horn CellsSignal TransductionSpinal CordVesicular Glutamate Transport Protein 2gamma-Aminobutyric AcidGlutamate Decarboxylaseglutamate decarboxylase 1NeuropeptidesNeurotransmitter AgentsVesicular Glutamate Transport Protein 2

Identifiers

PMID33664406
PMCPMC7933427
OpenAlexW3134112702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.