ArticleScientific reports2021
Transcriptional profiling of two contrasting genotypes uncovers molecular mechanisms underlying salt tolerance in alfalfa.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Physiological and transcriptomic analyses reveal the critical role of MsERF15 in negatively regulating cadmium stress tolerance in Alfalfa (Medicago sativa).Journal of plant research · 2026Article
- Adaptive Mechanisms of White-Flowered Alfalfa (Biology · 2026Article
- Genome-wide association study (GWAS) and transcriptome analysis reveal new candidate genes for leaf size in alfalfa.BMC plant biology · 2026Article
- Saline-Alkaline Stress-Driven Rhizobacterial Community Restructuring and Alleviation of Stress by Indigenous PGPR in Alfalfa.Plants (Basel, Switzerland) · 2025Article
- Alfalfa MsSOS2 confers salinity tolerance by promoting lateral root growth and regulating NaScientific reports · 2025Article
- Article
- Dynamic transcriptomics and physiological insights reveal multi-tissue salt adaptation mechanisms in Amaranthus hypochondriacus across stress gradients.Plant cell reports · 2025Article
- Global Transcriptomic Analysis of Inbred Lines Reveal Candidate Genes for Response to Maize Lethal Necrosis.Plants (Basel, Switzerland) · 2025Article
- Understanding abiotic stress in alfalfa: physiological and molecular perspectives on salinity, drought, and heavy metal toxicity.Frontiers in plant science · 2025Review
- Differential gene expression of salt-tolerant alfalfa in response to salinity and inoculation by Ensifer meliloti.BMC plant biology · 2024Article
- MsSPL12 is a positive regulator in alfalfa (Medicago sativa L.) salt tolerance.Plant cell reports · 2024Article
- Understanding the salt overly sensitive pathway in Prunus: Identification and characterization of NHX, CIPK, and CBL genes.The plant genome · 2024Article
- Strategies for combating plant salinity stress: the potential of plant growth-promoting microorganisms.Frontiers in plant science · 2024Review
- Comparative transcriptomic data confirm the findings of dehydration stress-induced redox biology of indigenous aromatic rice cultivars.3 Biotech · 2023Article
- Integrating Full-Length Transcriptome and RNA Sequencing of Siberian Wildrye (Plants (Basel, Switzerland) · 2023Article
- Elucidation of Physiological, Transcriptomic and Metabolomic Salinity Response Mechanisms inPlants (Basel, Switzerland) · 2023Article
- Transcriptome and Physio-Biochemical Profiling Reveals Differential Responses of Rice Cultivars at Reproductive-Stage Drought Stress.International journal of molecular sciences · 2023Article
- Photosynthesis and Salt Exclusion Are Key Physiological Processes Contributing to Salt Tolerance of Canola (Genes · 2022Article
- Combining QTL mapping and RNA-Seq Unravels candidate genes for Alfalfa (Medicago sativa L.) leaf development.BMC plant biology · 2022Article
- Morphological, physiological, biochemical, and transcriptome studies reveal the importance of transporters and stress signaling pathways during salinity stress in Prunus.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alfalfa is an important forage crop that is moderately tolerant to salinity; however, little is known about its salt-tolerance mechanisms. We studied root and leaf transcriptomes of a salt-tolerant (G03) and a salt-sensitive (G09) genotype, irrigated with waters of low and high salinities. RNA sequencing led to 1.73 billion high-quality reads that were assembled into 418,480 unigenes; 35% of which were assigned to 57 Gene Ontology annotations. The unigenes were assigned to pathway databases for understanding high-level functions. The comparison of two genotypes suggested that the low salt tolerance index for transpiration rate and stomatal conductance of G03 compared to G09 may be due to its reduced salt uptake under salinity. The differences in shoot biomass between the salt-tolerant and salt-sensitive lines were explained by their differential expressions of genes regulating shoot number. Differentially expressed genes involved in hormone-, calcium-, and redox-signaling, showed treatment- and genotype-specific differences and led to the identification of various candidate genes involved in salinity stress, which can be investigated further to improve salinity tolerance in alfalfa. Validation of RNA-seq results using qRT-PCR displayed a high level of consistency between the two experiments. This study provides valuable insight into the molecular mechanisms regulating salt tolerance in alfalfa.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.