Evidence map›Paper›PMID 33664334›Full record

ArticleScientific reports2021

Exercise training and burdock root (Arctium lappa L.) extract independently improve abdominal obesity and sex hormones in elderly women with metabolic syndrome.

Min-Seong Ha, Jang Soo Yook, Minchul Lee, Kazuya Suwabe, Woo-Min Jeong, Jae-Jun Kwak, Hideaki Soya

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Unveiling the Antihyperglycemic Potential ofFoods (Basel, Switzerland) · 2026
    Review
  2. Heliyon · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Min-Seong Ha *Department of Sports Culture, College of the Arts, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Jung-gu, Seoul, 04620, Republic of Korea. haminseong@dgu.ac.kr.
Jang Soo Yook *Center for Functional Connectomics, Brain Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul, 02792, Republic of Korea.
Minchul LeeDepartment of Sports Medicine, College of Health Science, CHA University, 120 Haeryong-ro, Pocheon-si, Gyeonggi-do, 11160, Republic of Korea.
Kazuya SuwabeDivision of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan.
Woo-Min JeongWellCare Korea Co. Ltd., 26 Wadong-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15265, Republic of Korea.
Jae-Jun KwakDepartment of National Defense Technology, Woosuk University, Daehak-ro 66, Jincheon-eup, Jincheon-gun, Chungcheongbuk-do, 27841, Republic of Korea.
Hideaki SoyaDivision of Sports Neuroscience, Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8574, Japan. soya.hideaki.gt@u.tsukuba.ac.jp.
University of Tsukuba · JPCHA University · KRDongguk University · KRKorea Institute of Science and Technology · KRWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of metabolic syndrome (MS) is increasing among the elderly, and new lifestyle-based treatment strategies are warranted. We conducted a randomized, double-blind controlled trial of the effects of aquatic exercise (AE) and/or consumption of burdock root extract (BE) on body composition and serum sex hormones, i.e., testosterone, estradiol, sex hormone-binding globulin (SHBG), and dehydroepiandrosterone-sulfate (DHEA-S) in elderly women with MS. The percentage of abdominal fat was decreased in the AE group. Waist circumference was increased in the control (CON) group, but not in the other groups. SHBG and estradiol levels were enhanced by both AE and BE and correlated with changes in fat-related body composition. DHEA-S levels only increased in the BE group, which was consistent with changes in lean body mass. Testosterone levels decreased in the CON group, which correlated with changes in lean body mass, skeletal muscle mass, body fat, and waist circumference. Our findings suggested that the combined AE/BE intervention exerted no synergistic and/or additive effects on any sex-related outcome measures in elderly women with MS.

Indexed as

ExerciseAgedArctiumBody Mass IndexFemaleGonadal Steroid HormonesHumansMetabolic SyndromeObesity, AbdominalPlant ExtractsPlant RootsSex Hormone-Binding GlobulinGonadal Steroid HormonesPlant ExtractsSex Hormone-Binding GlobulinSHBG protein, human

Identifiers

PMID33664334
PMCPMC7933410
OpenAlexW3135815280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.