Evidence map›Paper›PMID 33664121›Full record

ArticleBMJ open respiratory research2021

Typical within and between person variability in non-invasive ventilator derived variables among clinically stable, long-term users.

Vishnu Jeganathan, Linda Rautela, Simon Conti, Krisha Saravanan, Alyssa Rigoni, Marnie Graco, Liam M Hannan, Mark E Howard, David J Berlowitz

Abstract read
In one paragraph

Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Monitoring Systems in Home Ventilation.Journal of clinical medicine · 2023
    Review
  4. Telemonitoring for Home-assisted Ventilation: A Narrative Review.Annals of the American Thoracic Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vishnu JeganathanRespiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia.
Linda RautelaRespiratory and Sleep Medicine, Institute for Breathing and Sleep, Heidelberg, Victoria, Australia.
Simon ContiRespiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia.
Krisha SaravananRespiratory and Sleep Medicine, Institute for Breathing and Sleep, Heidelberg, Victoria, Australia.
Alyssa RigoniRespiratory and Sleep Medicine, Institute for Breathing and Sleep, Heidelberg, Victoria, Australia.
Marnie GracoInstitute for Breathing and Sleep, Heidelberg, Victoria, Australia.
Liam M HannanRespiratory and Sleep Medicine, Institute for Breathing and Sleep, Heidelberg, Victoria, Australia.
Mark E HowardRespiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia.
David J BerlowitzRespiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia david.berlowitz@austin.org.au.ORCID 0000-0003-2543-8722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite increasing capacity to remotely monitor non-invasive ventilation (NIV), how remote data varies from day to day and person to person is poorly described.

methodsSingle-centre, 2-month, prospective study of clinically stable adults on long-term NIV which aimed to document NIV-device variability. Participants were switched to a ventilator with tele-monitoring capabilities. Ventilation settings and masking were not altered. Raw, extensible markup language data files were provided directly from Philips Respironics (EncoreAnywhere). A nested analysis of variance was conducted on each ventilator variable to apportion the relative variation between and within participants.

resultsTwenty-nine people were recruited (four withdrew, one had insufficient data for analyses; 1364 days of data). Mean age was 54.0 years (SD 18.4), 58.3% male with body mass index of 37.0 kg/m

interpretationIn this clinically stable cohort, all device-derived indices were more varied between users than the day-to-day variation within individuals. We speculate that normative ranges and thresholds for clinical intervention need to be individualised, and further research is necessary to determine the clinically important relationships between clinician targets for therapy and patient-reported outcomes.

Indexed as

Noninvasive VentilationVentilators, MechanicalAdultFemaleHumansMaleMiddle AgedProspective StudiesRespiration, ArtificialTidal Volumeassisted ventilationclinical epidemiologynon invasive ventilation

Identifiers

PMID33664121
PMCPMC7934749

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.