SynthesisAJNR. American journal of neuroradiology2021
Do Outcomes between Women and Men Differ after Endovascular Thrombectomy? A Meta-analysis.
Synthesis in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Sex Differences in Screening for Large Vessel Occlusion and Thrombectomy: A Population-Based Cohort Study.Stroke · 2026Article
- Impact of Sex on In-Hospital Mortality and Discharge Disposition among Renal Failure Patients Undergoing Mechanical Thrombectomy for Acute Ischemic Stroke.Neurointervention · 2026Article
- Epidemiology and risk factors of stroke in the Americas: a comprehensive narrative literature review.Lancet regional health. Americas · 2026Review
- Sex differences in risk factors, stroke etiology, treatment characteristics, and outcomes after endovascular treatment for anterior circulation ischemic stroke.Frontiers in stroke · 2026Article
- Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry.European stroke journal · 2025Article
- Sex Differences in Prognostic Markers: Exploring Outcome Variability After Mechanical Thrombectomy in Large Vessel Occlusion Stroke.Journal of clinical medicine · 2025Article
- Retrospective analysis of a tertiary care centre of sex differences in risk factors, aetiology and short-term clinical outcome after revascularization treatment in young adults' ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Sex-Related Differences in Outcomes of Endovascular Treatment in Large Vessel Occlusion Stroke-Analyses From the German Stroke Registry-Endovascular Treatment.European journal of neurology · 2025Observational
- Evaluation of sex-based differences in below-the-knee plaque histology in patients who underwent amputation for chronic limb-threatening ischemia.JVS-vascular science · 2025Article
- Impact of Sex on Clinical Outcomes of Tandem Occlusion in Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy. A Propensity-Matched Analysis.European journal of neurology · 2025Observational
- Sex differences in clot, vessel and tissue characteristics in patients with a large vessel occlusion treated with endovascular thrombectomy.European stroke journal · 2024Article
- Post-Thrombectomy Subarachnoid Hemorrhage: Incidence, Predictors, Clinical Relevance, and Effect Modulators.Diagnostics (Basel, Switzerland) · 2024Article
- Sex-Specific Effects of Endovascular Treatment in Large-Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2024Article
- Impact of Sex on Thrombectomy Outcomes in Ischemic Stroke: A Propensity Score-Matched Study, Systematic Review, and Meta-Analysis.Stroke (Hoboken, N.J.) · 2024Article
- Sex and hypertensive organ damage: stroke.Journal of human hypertension · 2023Review
- Sex Differences in the Evaluation and Treatment of Stroke.Handbook of experimental pharmacology · 2023Review
- Sex and Gender Differences in Stroke and Their Practical Implications in Acute Care.Journal of stroke · 2023Review
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResearch on the presence of sex-based differences in the outcomes of patients undergoing endovascular thrombectomy for acute ischemic stroke has reached differing conclusions. PURPOSE: This review aimed to determine whether sex influences the outcome of patients with large-vessel occlusion stroke undergoing endovascular thrombectomy. STUDY SELECTION: We performed a systematic review and meta-analysis of endovascular thrombectomy studies with either stratified cohort outcomes according to sex (females versus males) or effect size reported for the consequence of sex versus outcomes. We included 33 articles with 7335 patients. DATA ANALYSIS: We pooled ORs for the 90-day mRS score, 90-day mortality, symptomatic intracranial hemorrhage, and recanalization. DATA SYNTHESIS: Pooled 90-day good outcomes (mRS ≤ 2) were better for men than women (OR = 1.29; 95% CI, 1.09-1.53; LIMITATIONS: Moderate heterogeneity was found. Most studies included were retrospective in nature. In addition, the randomized trials included were not specifically designed to compare outcomes between sexes.
conclusionsWomen undergoing endovascular thrombectomy for large-vessel occlusion have inferior 90-day clinical outcomes. Sex-specific outcomes should be investigated further in future trials as well as pathophysiologic studies.
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