Evidence map›Paper›PMID 33664105›Full record

ArticleAJNR. American journal of neuroradiology2021

Ivy Sign in Moyamoya Disease: A Comparative Study of the FLAIR Vascular Hyperintensity Sign Against Contrast-Enhanced MRI.

L-X Wang, H Wang, F-B Hao, J-H Lv, S-H Zhang, D-S Han, X-B Bian, D-K Zhang, Y-N Lan, X-R Wang and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

L-X WangFrom the Medical School of Chinese PLA (L.-X.W., S.-H.Z., D.-S.H.), Beijing, China.ORCID 0000-0002-7655-0397
H WangDepartment of Neurosurgery (H.W., F.-B.H., L.D.), the Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-1152-5860
F-B HaoDepartment of Neurosurgery (H.W., F.-B.H., L.D.), the Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-5607-6926
J-H LvDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-5177-7640
S-H ZhangFrom the Medical School of Chinese PLA (L.-X.W., S.-H.Z., D.-S.H.), Beijing, China.ORCID 0000-0001-7537-876X
D-S HanFrom the Medical School of Chinese PLA (L.-X.W., S.-H.Z., D.-S.H.), Beijing, China.ORCID 0000-0002-4216-4869
X-B BianDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-7016-6503
D-K ZhangDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-9711-6733
Y-N LanDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-5569-7883
X-R WangDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-7003-4917
M-T WeiDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-2045-3117
L DuanDepartment of Neurosurgery (H.W., F.-B.H., L.D.), the Fifth Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-7210-056X
L MaDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China cjr.malin@vip.163.com.ORCID 0000-0002-2911-3653
X LouDepartment of Radiology (L.-X.W., J.-H.L., S.-H.Z., D.-S.H., X.-B.B., D.-K.Z., Y.-N.L., X.-R.W., M.-T.W., X.L., L.M.), the First Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0003-2980-5171
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe ability of the ivy sign on contrast-enhanced T1-weighted MR imaging (CEMR) to reflect cerebral perfusion and postoperative revascularization in Moyamoya disease remains largely unknown. We aimed to compare the capabilities of CEMR and FLAIR. MATERIALS AND

methodsCEMR, FLAIR, arterial spin-labeling, and DSA were performed in 44 patients with Moyamoya disease. The ivy sign was scored separately on CEMR and FLAIR using the Alberta Stroke Program Early CT Score. The status of leptomeningeal collaterals was scored on DSA. The postoperative Matsushima grade was evaluated at least 3 months after surgical revascularization.

resultsScoring of the ivy sign on CEMR showed excellent interrater reliability, and FLAIR vascular hyperintensity showed moderate interrater reliability. Correlation analyses revealed that DSA scores were more consistent with the CEMR-based ivy sign score (

conclusionsIn this study, CEMR outperformed FLAIR in capturing the ivy sign in Moyamoya disease. In addition, the CEMR-based ivy sign score provided adequate information on hemodynamic status and postoperative neovascularization. The current study suggested that CEMR could be considered as an alternative to FLAIR in future studies investigating leptomeningeal collaterals in Moyamoya disease.

Indexed as

Moyamoya DiseaseAdultFemaleHemodynamicsHumansMagnetic Resonance ImagingMaleMeningesMiddle AgedReproducibility of Results

Identifiers

PMID33664105
PMCPMC8040985
OpenAlexW3135166331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.