ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021
Ambulatory Function and Mortality among Cancer Survivors in the NIH-AARP Diet and Health Study.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Effects of a DVD-delivered randomized controlled physical activity intervention on functional health in cancer survivors.BMC cancer · 2021Trial
- Criterion Validity of a Consumer Wearable for Step Counting and Activity Intensity Classification in Adults With Lung Cancer: Laboratory-Based Validation Study.JMIR formative research · 2026Article
- Associations of sarcopenia, sarcopenia components and sarcopenic obesity with cancer incidence: A prospective cohort study of 414,094 participants in UK Biobank.International journal of cancer · 2025Article
- Exploring the prevalence of atopic disease among adult cancer survivors: insights from the 2021 NHIS.PloS one · 2025Article
- Extended Reality Gaming for Exercise and Mindfulness Throughout Pediatric Cancer Rehabilitation: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2024Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThere is limited evidence describing associations between cancer and function in diverse cancer types and its relationship with mortality. We investigated the relationship between cancer and poor ambulatory function and associations between ambulatory function and subsequent mortality.
methodsParticipants included 233,135 adults (
resultsSurvivors had 42% greater odds of walking at the slowest pace [OR, 1.42 (confidence interval (CI), 1.30-1.54)] and 24% greater odds of mobility disability [OR, 1.24 (CI, 1.17-1.31)], compared with cancer-free participants, adjusting for baseline demographics, health indicators, and cancer type. Survivors reporting the slowest pace were at increased hazards than those who walked the fastest: all-cause mortality [HR, 2.22 (CI, 2.06-2.39)] and cancer mortality [HR, 2.12 (CI, 1.83-2.45)]. Similar trends emerged for mobility disability (HRs > 1.64). All-cause mortality associations were significant for more than nine cancer types.
conclusionsA diagnosis of cancer is associated with poorer ambulatory function, which is subsequently associated with increased mortality. IMPACT: Widespread efforts should target ambulatory function during cancer survivorship for survival benefits.
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