Observational studyJACC. Cardiovascular interventions2021
Tip-to-Base LAMPOON for Transcatheter Mitral Valve Replacement With a Protected Mitral Annulus.
Observational study in JACC. Cardiovascular interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Mitral Valve Leaflet Modification: A Working Group Position Statement on Best Practices and Step-by-Step Guide.JACC. Cardiovascular interventions · 2026Guideline
- Current Evidence, Emerging Evidence, and Decision-Making: An Algorithm for Leaflet Modification Procedures.JACC. Cardiovascular interventions · 2026Review
- LAMPOON Followed by Valve-in-Valve-in-Ring for Transcatheter Mitral Valve Replacement.CASE (Philadelphia, Pa.) · 2026Article
- Review
- Annular Reduction by Cinching With TEER in Commissure in Conventionally Inappropriate Ring for Transcatheter Valve.JACC. Case reports · 2025Article
- Transesophageal Echocardiography in Transcatheter Mitral Valve Replacement.Journal of clinical medicine · 2025Review
- Retrograde Balloon-Induced Anterior Mitral Leaflet Laceration: The ROBIN Technique.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Advances in Transcatheter Mitral Valve Replacement (TMVR) in Patients with Mitral Annular Calcification: A Case Report of Acute Hemolytic Anemia and Review of Contemporary Approaches.Journal of clinical medicine · 2025Review
- Expanding the Toolbox for Transcatheter Mitral Valve-in-Ring Interventions.JACC. Case reports · 2025Article
- Kissing Balloon Dilatation of a Transcatheter Mitral Valve Replacement Within an Extra-Large D-Shaped Annuloplasty Ring.JACC. Case reports · 2025Article
- Prevention of left ventricular outflow tract obstruction in transapical mitral valve replacement: the MitraCut procedure.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
- Devices and approaches for leaflet modification.JTCVS structural and endovascular · 2024Article
- A Modified Tip-to-Base LAMPOON to Prevent Left Ventricular Outflow Tract Obstruction in Valve-in-Ring or Valve-in-Valve Transcatheter Mitral Valve Replacement.Acta Cardiologica Sinica · 2024Article
- Transcatheter mitral valve implantation for native valve disease.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Review
- Novel technique to prevent outflow tract obstruction in transapical transcatheter mitral valve replacement: The MitraCut technique.JTCVS techniques · 2023Article
- Transcatheter Electrosurgery: A Narrative Review.Circulation. Cardiovascular interventions · 2023Review
- Use of Electrosurgery in Interventional Cardiology.Interventional cardiology clinics · 2022Review
- Transcatheter Myotomy to Relieve Left Ventricular Outflow Tract Obstruction: The Septal Scoring Along the Midline Endocardium Procedure in Animals.Circulation. Cardiovascular interventions · 2022Article
- The Art of SAPIEN 3 Transcatheter Mitral Valve Replacement in Valve-in-Ring and Valve-in-Mitral-Annular-Calcification Procedures.JACC. Cardiovascular interventions · 2021Review
- Use of transesophageal echocardiography for transcatheter valve-in-valve implantation for patients with prior bioprosthetic surgical aortic, mitral, tricuspid, and pulmonic valves.Annals of cardiothoracic surgery · 2021Review
Corrections and comments
- Commented on by
- Erratum issuedCorrection.2021
Authors and funding
28 authors at 12 institutions in 1 country.
Funding
Abstract
objectivesThe purpose of this study was to evaluate tip-to-base intentional laceration of the anterior mitral leaflet to prevent left ventricular outflow tract obstruction (LAMPOON) in patients undergoing transcatheter mitral valve replacement (TMVR) in annuloplasty rings or surgical mitral valves.
backgroundLAMPOON is an effective adjunct to TMVR that prevents left ventricular outflow tract obstruction (LVOTO). Laceration is typically performed from the base to the tip of the anterior mitral leaflet. A modified laceration technique from leaflet tip to base may be effective in patients with a prosthesis that protects the aortomitral curtain.
methodsThis is a multicenter, 21-patient, consecutive retrospective observational cohort. Patients underwent tip-to-base LAMPOON to prevent LVOTO and leaflet overhang, or therapeutically to lacerate a long anterior mitral leaflet risking or causing LVOTO. Outcomes were compared with findings from patients in the LAMPOON investigational device exemption trial with a prior mitral annuloplasty.
resultsTwenty-one patients with a annuloplasty or valve prosthesis-protected mitral annulus underwent tip-to-base LAMPOON (19 preventive, 2 rescue). Leaflet laceration was successful in all and successfully prevented or treated LVOTO in all patients. No patients had significant LVOTO upon discharge. There were 2 cases of unintentional aortic valve injury (1 patient underwent emergency transcatheter aortic valve replacement and 1 patient underwent urgent surgical aortic valve replacement). In both cases, the patients had a supra-annular ring annuloplasty, and the retrograde aortic guiding catheter failed to insulate the guidewire lacerating surface from the aortic root. All patients survived to 30 days. Compared with classic retrograde LAMPOON, there was a trend toward shorter procedure time.
conclusionsTip-to-base laceration is a simple, effective, and safe LAMPOON variant applicable to patients with an appropriately positioned mitral annular ring or bioprosthetic valve. Operators should take care to insulate the lacerating surface from adjacent structures.
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