Trial reportArthritis research & therapy2021
The effects of WeChat-based educational intervention in patients with ankylosing spondylitis: a randomized controlled trail.
Trial report in Arthritis research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06450600 (Enhancing Quality of Life in Multiple Sclerosis), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enhancing Quality of Life in Multiple Sclerosis: a Study Protocol to Evaluate the Impact of a Therapeutic Education Program
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Randomized controlled trials of digital health interventions for rheumatic disease management: a systematic review.Bulletin of the World Health Organization · 2025Pooled it
- Continuity of care in lumbar disc herniation: a systematic review and meta-analysis providing a deeper look into postoperative efficacy.Frontiers in medicine · 2025Pooled it
- The Impact of a Theory-Based mHealth Intervention on Disease Knowledge, Self-efficacy, and Exercise Adherence Among Ankylosing Spondylitis Patients: Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Behavioral Determinants Potentially Relevant to First-Witness Responses in Prehospital Stroke Care: A COM-B-Based Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Impact of interventions to prevent anxiety and depression in people with inflammatory rheumatological conditions: a systematic review.Rheumatology advances in practice · 2026Review
- Obesity Prevention and Reduction in China Using the Social Media Platform WeChat: Scoping Review.Interactive journal of medical research · 2025Review
- The impact of nurse-led disease management education on outcomes of patients with ankylosing spondylitis: a randomised controlled trial.Journal of research in nursing : JRN · 2025Article
- Enhancing quality of life in multiple sclerosis: A study protocol to evaluate the impact of a therapeutic education program.Journal of education and health promotion · 2025Article
- Evidence for telemedicine heterogeneity in rheumatic and musculoskeletal diseases care: a scoping review.Clinical rheumatology · 2024Article
- Effectiveness of Digital Mental Health Tools to Reduce Depressive and Anxiety Symptoms in Low- and Middle-Income Countries: Systematic Review and Meta-analysis.JMIR mental health · 2023Review
- Future challenges in rheumatology - is telemedicine the solution?Therapeutic advances in musculoskeletal disease · 2022Review
- Correction to: The effects of WeChat-based educational intervention in patients with ankylosing spondylitis: a randomized controlled trial.Arthritis research & therapy · 2021Article
- Predictors of Health-Related Quality of Life in Patients with Ankylosing Spondylitis in Southwest China.Patient preference and adherence · 2021Article
- Development and usability evaluation of a culturally adapted stroke prevention educational programme on WeChat apps.Digital healthArticle
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnkylosing spondylitis (AS), as a common inflammatory rheumatic disease, often causes depression and impaired health-related quality of life (QoL). Although positive effects of patient education have been demonstrated, limited studies explored the benefits of education via mobile applications for AS patients. This study aimed to evaluate the effects of the WeChat-based educational intervention on depression, health-related QoL, and other clinical outcomes in AS patients.
methodsWe conducted a single-blind randomized controlled trial from March to December 2017. Patients were recruited and randomized into the intervention group which received a 12-week WeChat-based educational intervention (consisting of four individual online educational sessions, online educational materials) or the control group receiving standard care. Data was collected at baseline and 12 weeks. Outcomes were measured by Beck Depression Inventory-II, the Medical Outcomes Study Short Form 36-item Health Survey (SF-36), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Patient Global Score (BAS-G), and visual analog scales.
resultsA total of 118 patients with AS were included and analyzed. Measures at baseline were comparable between groups. After the intervention, the intervention group reported significant higher scores of all domains of SF-36 except for physical functioning and validity, compared with the control group. Additionally, patients in the intervention group had lower depressive symptoms than the control group. No significant difference in other outcomes was observed at 12 weeks.
conclusionsThis study found that the 12-week educational intervention via WeChat had positive effects on reducing depressive symptoms and improving health-related QoL in Chinese patients with AS. We suggest that this intervention can be integrated into current routine care of AS patients.
trial registrationThis study has been approved by the hospital's ethics committee (ID: 20160364) in 2016 and registered at the Chinese Clinical Trail Registry (registry number: ChiCTR-IPR-16009293 ).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.