SynthesisBMC health services research2021
Learning health systems using data to drive healthcare improvement and impact: a systematic review.
Synthesis in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
128 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Relationship between staff experience and patient outcomes in hospital settings: an overview of reviews.BMJ open · 2025Pooled it
- An Exploration of the Utility and Impacts of Implementation Science Strategies by Cancer Registries for Healthcare Improvement: A Systematic Review.International journal of health policy and management · 2024Pooled it
- Learning Health Systems and Substance Use Care Cascade Achievement Among Justice-Involved Youth: A Cluster-Randomized Stepped-Wedge Clinical Trial.JAMA network open · 2026Trial
- Learning Health System Implementation: Building a Hub-and-Spoke Model for Hypertension Management Through the QI Hub.Journal of general internal medicine · 2026Article
- Perspectives in Pediatric Ambulatory Anesthesia: Part 4-Evolving Solutions in Pediatric Ambulatory Anesthesia: From Registries to a Learning Health System Approach.Paediatric anaesthesia · 2026Review
- Toward a Smart Learning Health System: An Ontology-Based Framework.Learning health systems · 2026Article
- Delivering high-quality multiple sclerosis care in Germany: challenges and regional models.Neurological research and practice · 2026Review
- Measuring healthcare quality in police custody: the development of quality indicators through expert consultations in the Netherlands.Health & justice · 2026Article
- Article
- A scoping review of outcome and outcome measure sets for adults with spinal cord injury, stroke, and traumatic brain injury.Journal of rehabilitation medicine · 2026Article
- Implementation of a learning health system for the management of non-communicable diseases in Thailand: a realist evaluation protocol.BMJ open · 2026Article
- Advancing learning health care systems with best practice meetings: a mixed-methods study with insights from the Dutch Institute for Clinical Auditing.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2026Article
- Exploring Barriers, Enablers, and Strategies for Implementing Learning Health System Projects in Healthcare Organizations: A Multilevel Analysis in an Australian Setting.Learning health systems · 2026Article
- Supporting Cultural and Learning Enablers for a Learning Health System (SCALE): A Program Theory Approach.Learning health systems · 2026Article
- Factors Influencing Physician Adherence to Venous Thromboembolism Risk Assessment Model Recommendations: A Best-Worst Scaling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026Article
- Reducing unnecessary bed days to optimise flow and improve demand-capacity mismatch: learning from a system-wide patient flow collaborative.BMJ open quality · 2026Article
- Barriers to Leveraging Patient Safety Event Reviews for Organizational Learning, Improvement, and Diagnostic Error Reduction: Results of a Single Academic Center Survey Study.Journal of general internal medicine · 2026Article
- Heavy Metal Toxicity in Clinical and Environmental Health: Sources, Mechanisms, Diagnostics, and Evidence-Based Management of Mercury, Lead, Cadmium, and Arsenic.International journal of molecular sciences · 2026Review
- Concordance of Death Information Between Two Health Systems Serving the Same Region and the Social Security Administration Death Master File: Retrospective Observational Study.JMIR medical informatics · 2026Observational
- Navigating and reframing tensions within equity-centered learning health systems.Learning health systems · 2026Article
68 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe transition to electronic health records offers the potential for big data to drive the next frontier in healthcare improvement. Yet there are multiple barriers to harnessing the power of data. The Learning Health System (LHS) has emerged as a model to overcome these barriers, yet there remains limited evidence of impact on delivery or outcomes of healthcare.
objectiveTo gather evidence on the effects of LHS data hubs or aligned models that use data to deliver healthcare improvement and impact. Any reported impact on the process, delivery or outcomes of healthcare was captured.
methodsSystematic review from CINAHL, EMBASE, MEDLINE, Medline in-process and Web of Science PubMed databases, using learning health system, data hub, data-driven, ehealth, informatics, collaborations, partnerships, and translation terms. English-language, peer-reviewed literature published between January 2014 and Sept 2019 was captured, supplemented by a grey literature search. Eligibility criteria included studies of LHS data hubs that reported research translation leading to health impact.
resultsOverall, 1076 titles were identified, with 43 eligible studies, across 23 LHS environments. Most LHS environments were in the United States (n = 18) with others in Canada, UK, Sweden and Australia/NZ. Five (21.7%) produced medium-high level of evidence, which were peer-reviewed publications.
conclusionsLHS environments are producing impact across multiple continents and settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.