Evidence map›Paper›PMID 33663504›Full record

ArticleBMC veterinary research2021

Isolation and identification of Candida tropicalis in sows with fatal infection: a case report.

Lufeng Zhai, Ying Zhou, Yingxia Wu, Yunyun Jin, Qiaoyan Zhu, Shengguo Gao, Xuefeng Li, Zhe Sun, Yan Xiao, Baicheng Huang and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Infection by Histoplasma capsulatum and Candida tropicalis in a Coendou longicaudatus boliviensis (neotropical porcupine).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  2. Antifungal Drug Resistance.Current topics in microbiology and immunology · 2025
    Review
  3. Isolation and identification ofFrontiers in cellular and infection microbiology · 2024
    Article
  4. Article
  5. What IsMicroorganisms · 2022
    Review
  6. The emerging threat antifungal-resistantFrontiers in fungal biology · 2022
    Review
  7. Swine abortion caused by Candida parapsilosis.The Journal of veterinary medical science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lufeng ZhaiNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Ying ZhouNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Yingxia WuNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Yunyun JinNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Qiaoyan ZhuNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Shengguo GaoNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Xuefeng LiNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Zhe SunNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Yan XiaoNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China.
Baicheng HuangNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China. hbch228@163.com.
Kegong TianNational Research Center for Veterinary Medicine, No.3 Cuiwei Road, High-Tech District, 471003, Luoyang, Henan, PR China. vetvac@126.com.
Henan University of Science and Technology · CN

Funding

Special Project of Industrial Cluster in Self-created Zone in Zhengzhou, Luoyang, and Xinxiang Cities 181200211700
6 · The paper itself

Abstract

backgroundCandida is the common conditionally pathogenic fungus that infected human and animal clinically. C. tropicalis had been isolated from the skin and hair of healthy pigs, but with no report of fatal infection in gastrointestinal diseases. CASE PRESENTATION: In a pig farm in Henan Province of China, about 20 % of pregnant and postpartum sows suffered from severe gastrointestinal diseases, with a mortality rate higher than 60 % in the diseased animals. The sows had gastrointestinal symptoms such as blood in stool and vomiting. Necropsy revealed obvious gastric ulcers, gastrointestinal perforation, and intestinal hemorrhage in the gastrointestinal tract, but no lesions in other organs. The microbial species in gastric samples collected from gastric ulcer of the diseased sows then was initially identified as Candida by using routine systems of microscopic examination, culture characteristics on the medium Sabouraud dextrose agar medium. The fungus was further identified as C. tropicalis by species-specific PCR and sequencing. This study revealed an infection of C. tropicalis in sows through gastrointestinal mucosa could cause fatal digestive system disease and septicemia.

conclusionsFor the first time, a strain of C. tropicalis was isolated and identified from the gastric tissue of sows with severe gastrointestinal diseases. PCR and sequencing of ITS-rDNA combined with morphology and histopathological assay were reliable for the identification of Candida clinically.

Indexed as

Animal FeedAnimalsCandida tropicalisCandidiasisChinaDNA, RibosomalFemaleGastrointestinal DiseasesPolymerase Chain ReactionSwineSwine DiseasesDNA, Ribosomal

Identifiers

PMID33663504
PMCPMC7934564
OpenAlexW3135772891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.