ArticleRespiratory research2021
Predictors of mortality in COPD exacerbation cases presenting to the respiratory intensive care unit.
Article in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Chronic Obstructive Pulmonary Disease and the Management of Cardiopulmonary Risk in the UK: A Systematic Literature Review and Modified Delphi Study.International journal of chronic obstructive pulmonary disease · 2025Pooled it
- Narrative Review of the Bacterial Profile Involved in Severe COPD Exacerbations Complicated by Pneumonia in Patients Admitted to the Intensive Care Unit.Journal of clinical medicine · 2026Review
- Metagenomic Next-Generation Sequencing for Pulmonary Tuberculosis Diagnosis and Infection Risk Factor Analysis in AECOPD Patients: A Single-Center Retrospective Study.Journal of clinical medicine · 2026Article
- Validated prediction model for in hospital mortality in AECOPD with type 2 diabetes.Scientific reports · 2026Article
- Specialty-led inpatient chronic obstructive pulmonary disease management and mortality: a propensity-weighted cohort study.Journal of thoracic disease · 2026Article
- Construction and internal-external validation of a machine learning-based risk prediction model for multidrug resistance in ICU patients with acute exacerbation of chronic obstructive pulmonary disease.Frontiers in medicine · 2026Article
- Variation in inpatient investigations and treatment practices for COPD exacerbations between respiratory and internal medicine specialties: a retrospective cohort study.Frontiers in medicine · 2026Article
- Explainable machine learning model for 1-year readmission risk prediction in AECOPD patients: integrating relief feature selection with sample augmentation.BMC infectious diseases · 2025Article
- Predictive value of platelet to lymphocyte ratio for in-hospital outcome of patients admitted with diagnosis of exacerbation of COPD with type II respiratory failure.Annals of medicine and surgery (2012) · 2025Article
- Resources and Readmission for COPD Exacerbation in Pneumology Units in Spain: The COPD Observatory Project.Healthcare (Basel, Switzerland) · 2025Article
- Predictive score for in-hospital mortality in patients with severe acute exacerbations of chronic obstructive pulmonary disease.Archives of medical science : AMS · 2025Article
- Blood Eosinophil Stability Predicts Clinical Outcomes in Hospitalized Patients with Acute Exacerbations of COPD.International journal of chronic obstructive pulmonary disease · 2025Article
- An enhanced machine learning-based prognostic prediction model for patients with AECOPD on invasive mechanical ventilation.iScience · 2024Article
- Triggers of intensive care patients with palliative care needs from nurses' perspective: a mixed methods study.Critical care (London, England) · 2024Article
- A simple clinical risk score (ABCDMP) for predicting mortality in patients with AECOPD and cardiovascular diseases.Respiratory research · 2024Article
- Respiratory Infection Triggering Severe Acute Exacerbations of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2024Article
- Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients.ERJ open research · 2024Article
- [Epidemiology and hospitalization costs analysis of female inpatients with acute exacerbation of chronic obstructive pulmonary disease in Beijing from 2013 to 2020].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Clinical Outcomes according to Timing to Non Invasive Ventilation Initiation in COPD Patients with Acute Respiratory Failure: A Retrospective Cohort Study.Journal of clinical medicine · 2023Article
- Hematological Parameters for Predicting Mortality in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundStudies report high in-hospital mortality of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) especially for those requiring admission to an intensive care unit. Recognizing factors associated with mortality in these patients could reduce health care costs and improve end-of-life care.
methodsThis retrospective study included AECOPD patients admitted to the respiratory intensive care unit of a tertiary hospital in Beijing from Jan 1, 2011 to Dec 31, 2018. Patients demographic characteristics, blood test results and comorbidities were extracted from the electronic medical record system and compared between survivors and non-survivors.
resultsWe finally enrolled 384 AECOPD patients: 44 (11.5%) patients died in hospital and 340 (88.5%) were discharged. The most common comorbidity was respiratory failure (294 (76.6%)), followed by hypertension (214 (55.7%)), coronary heart disease (115 (29.9%)) and chronic heart failure (76 (19.8%)). Multiple logistic regression analysis revealed that independent risk factors associated with in-hospital mortality included lymphocytopenia, leukopenia, chronic heart failure and requirement for invasive mechanical ventilation.
conclusionsThe in-hospital mortality of patients with acute COPD exacerbation requiring RICU admission is high. Lymphocytes < 0.8 × 10
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.