Evidence map›Paper›PMID 33663427›Full record

ArticleBMC cancer2021

Central neck lymph node metastasis in oral squamous cell carcinoma at the floor of mouth.

Songtao Zhang, Runfang Zhang, Chao Wang, Wenbo Gong, Miaomiao Xue, Lina Liu, Yuanyuan Zhang

Abstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. A nomogram for predicting overall survival of patients with squamous cell carcinoma of the floor of the mouth: a population-based study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Songtao ZhangDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Runfang ZhangDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Chao WangDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Wenbo GongDepartment of Thyroid Head and Neck Surgery, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
Miaomiao XueDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, China.
Lina LiuDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, China.
Yuanyuan ZhangDepartment of General Dentistry, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, China. zhyy143@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur goal was to analyze the incidence of level VI metastasis in previously untreated oral squamous cell carcinoma (SCC) patients and their clinicopathological and prognostic characteristics.

methodsOral SCC patients with level VI metastasis were retrospectively enrolled, and their demographic and pathologic features as well as their survival data were descriptively analyzed.

resultsA total of 13 cases from 1875 patients were included, all patients had SCC at the floor of mouth (SCCFOM). Eight (61.5%) patients had a pT4 tumor, and all patients had a pathological N3 neck with multiple positive lymph nodes. Adverse pathologic features were present in 100% of the patients. The size of the metastatic foci in level VI ranged from 2.6 cm to 4.5 cm with a mean value of 3.2 cm, and 5 patients showed a soft tissue deposit with no lymph node component. Recurrence occurred in all patients, and 11 patients died of uncontrolled cancer within 5 years after surgery.

conclusionLevel VI metastasis in primary oral SCCFOM is rare, and its prognosis is poor.

Indexed as

AdultAgedHumansLymphatic MetastasisMaleMiddle AgedMouth FloorMouth NeoplasmsNeckSquamous Cell Carcinoma of Head and NeckCentral neck metastasisHead and neck squamous cell carcinomaLevel VI metastasisNeck lymph node metastasisOral squamous cell carcinoma

Identifiers

PMID33663427
PMCPMC7934489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.