Evidence map›Paper›PMID 33663391›Full record

ArticleBMC anesthesiology2021

General versus regional anaesthesia for caesarean section indicated for acute foetal distress: a retrospective cohort study.

Junette Arlette Mbengono Metogo, Theophile Njamen Nana, Brian Ajong Ngongheh, Emelinda Berinyuy Nyuydzefon, Christoph Akazong Adjahoung, Joel Noutakdie Tochie, Jacqueline Ze Minkande

Registry-linked trialOpen access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06160583 (General Anesthesia in Obstetric Patients for Cesarean Section, Maternal and Perinatal Outcomes), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06160583 completednot on this mapstarted 2023, after this paper: background citation

General Anesthesia in Obstetric Patients for Cesarean Section, Maternal and Perinatal Outcomes

Typeobservational_patient_registrySponsorHospital Civil de GuadalajaraRan2023 to 2024Enrolled5,000ConditionsAnesthesia, Perinatal Morbidity, Maternal-Fetal Relations
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Junette Arlette Mbengono MetogoDepartment of Anaesthesiology and Critical Care, Douala General Hospital, Douala, Cameroon.
Theophile Njamen NanaDepartment of Obstetrics and Gynaecology, Douala General Hospital, Douala, Cameroon.
Brian Ajong NgonghehMigration Health Department, International Organization for Migration (IOM) Country Program, Kinshasa, Democratic Republic of Congo.
Emelinda Berinyuy NyuydzefonDepartment of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon. nberinyuy@yahoo.com.
Christoph Akazong AdjahoungDepartment of Paediatrics, Douala General Hospital, Douala, Cameroon.
Joel Noutakdie TochieDepartment of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Jacqueline Ze MinkandeDepartment of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Université de Yaoundé I · CMUniversity of Douala · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute foetal distress (AFD) is a life-threatening foetal condition complicating 2% of all pregnancies and accounting for 8.9% of caesarean sections (CS) especially in developing nations. Despite the severity of the problem, no evidence exists as to the safest anaesthetic technique for the mother and foetus couple undergoing CS for AFD. We aimed to compare general anaesthesia (GA) versus regional (spinal and epidural) anaesthesia in terms of their perioperative maternal and foetal outcomes.

methodsWe carried out a retrospective cohort study by reviewing the medical records of all women who underwent CS indicated for AFD between 2015 to 2018 at the Douala General Hospital, Cameroon. Medical records of neonates were also reviewed. We sought to investigate the association between GA, and regional anaesthesia administered during CS for AFD and foetal and maternal outcomes. The threshold of statistical significance was set at 0.05.

resultsWe enrolled the medical records of 117 pregnant women who underwent CS indicated for AFD. Their mean age and mean gestational age were 30.5 ± 4.8 years and 40 weeks respectively. Eighty-three (70.9%), 29 (24.8%) and 05 (4.3%) pregnant women underwent CS under SA, GA and EA respectively. Neonates delivered by CS under GA were more likely to have a significantly low APGAR score at both the 1st (RR = 1.93, p = 0.014) and third-minute (RR = 2.52, p = 0.012) and to be resuscitated at birth (RR = 2.15, p = 0.015). Past CS, FHR pattern on CTG didn't affect these results in multivariate analysis. Adverse maternal outcomes are shown to be higher following SA when compared to GA.

conclusionThe study infers an association between CS performed for AFD under GA and foetal morbidity. This, however, failed to translate into a difference in perinatal mortality when comparing GA vs RA. This finding does not discount the role of GA, but we emphasize the need for specific precautions like adequate anticipation for neonatal resuscitation to reduce neonatal complications associated with CS performed for AFD under GA.

Indexed as

Acute DiseaseAdolescentAdultAnesthesia, ConductionAnesthesia, GeneralAnesthesia, ObstetricalApgar ScoreCesarean SectionCohort StudiesFemaleFetal DistressHumansPregnancyRetrospective StudiesYoung AdultAcute foetal distressAnaesthesiaCaesarean sectionMaternalNeonatalOutcome

Identifiers

PMID33663391
PMCPMC7931547
OpenAlexW3114418198

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.