Evidence map›Paper›PMID 33662269›Full record

ArticleNeuron2021

Dissecting the neural circuitry of fear-induced appetite suppression.

Jessica Shaw, Mariella De Biasi

Open access · bronzeAbstract readComment
In one paragraph

Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jessica ShawDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mariella De BiasiDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: marielde@pennmedicine.upenn.edu.
University of Pennsylvania · US

Funding

Striatal mechanisms for e-cigarette reinforcement by flavorantsR01DA049545 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI DE BIASI, MARIELLA, MA, MINGHONG · 2019 to 2023
$3.2M
Flavored e-cigarette use in adolescents: Behavioral, cellular, and epigenetic mechanismsR01DA044205 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI DE BIASI, MARIELLA · 2018 to 2022
$2.2M
NIDA NIH HHS R01 DA044205NIDA NIH HHS R01 DA049545
6 · The paper itself

Abstract

The circuit that links stress and fear to feeding behavior is poorly understood. In this issue of Neuron, Yang et al. detail a trisynaptic, cannabinoid-dependent circuit that underlies appetite suppression in response to a fearful stimulus and provide evidence of noradrenaline and glutamate co-transmission in locus coeruleus.

Indexed as

AppetiteLocus CoeruleusFearNeuronsNorepinephrineNorepinephrine

Identifiers

PMID33662269
PMCPMC8203095
OpenAlexW3135557650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.