Evidence map›Paper›PMID 33661475›Full record

ArticleAnnals of nuclear medicine2021

High detection rate in [

Tadashi Watabe, Motohide Uemura, Fumihiko Soeda, Sadahiro Naka, Takeshi Ujike, Koji Hatano, Hidetaka Sasaki, Takashi Kamiya, Eku Shimosegawa, Hiroki Kato and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Annals of nuclear medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Contrast media & molecular imaging · 2021
    Pooled it
  4. Diagnostic impact of interpretation criteria for [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. [International journal of urology : official journal of the Japanese Urological Association · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. [Diagnostics (Basel, Switzerland) · 2024
    Article
  11. Evaluation ofAnnals of nuclear medicine · 2024
    Article
  12. Preclinical Evaluation of Biodistribution and Toxicity of [International journal of molecular sciences · 2024
    Article
  13. Detection support of lesions in patients with prostate cancer usingInternational journal of computer assisted radiology and surgery · 2024
    Article
  14. Article
  15. Targeted α-therapy using astatine (European journal of nuclear medicine and molecular imaging · 2023
    Article
  16. The current status of prostate cancer treatment and PSMA theranostics.Therapeutic advances in medical oncology · 2023
    Review
  17. Article
  18. Recurrent Prostate Cancer Diagnostics withDiagnostics (Basel, Switzerland) · 2022
    Review
  19. Biokinetics and dosimetry ofClinical physiology and functional imaging · 2022
    Article
  20. Predictors ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. watabe@tracer.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0001-8658-2395
Motohide UemuraDepartment of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Fumihiko SoedaDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Sadahiro NakaDepartment of Radiology, Osaka University Hospital, Osaka, Japan.
Takeshi UjikeDepartment of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Koji HatanoDepartment of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Hidetaka SasakiDepartment of Radiology, Osaka University Hospital, Osaka, Japan.
Takashi KamiyaDepartment of Radiology, Osaka University Hospital, Osaka, Japan.
Eku ShimosegawaInstitute for Radiation Sciences, Osaka University, Osaka, Japan.
Hiroki KatoDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Jens CardinaleDepartment of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Ukihide TateishiDepartment of Diagnostic Radiology, Medical Hospital, Tokyo Medical and Dental University, Tokyo, Japan.
Norio NonomuraDepartment of Urology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Frederik L GieselInstitute for Radiation Sciences, Osaka University, Osaka, Japan.
The University of Osaka · JPOsaka University Hospital · JPHeidelberg University · DETokyo Medical and Dental University Hospital · JP

Funding

Japan Science and Technology Agency (JST) JPMJOP1721
6 · The paper itself

Abstract

objective

methodsWe enrolled a total of 28 patients (age 51-79 years) with BCR of prostate cancer. BCR was defined as a continuous increase in PSA after radical prostatectomy or radiation therapy without any apparent recurrent lesions on conventional diagnostic imaging (CT and bone scintigraphy). PSMA-PET scanning was performed approximately 60 min after intravenous injection of [

resultsAbnormal uptake, which was suspected to be recurrence or metastasis, was detected in 92.9% (26/28) of patients with BCR. The SUVmax was 8.4 ± 6.4 in local recurrence, 11.5 ± 11.8 in pelvic lymph nodes (LN), and 4.1 ± 1.6 in bone metastasis. The detection rates were 66.7% in the PSA group-1 (0.1-0.5 ng/mL), 85.7% in the PSA group-2 (0.5-1.0 ng/mL), and 100% in the PSA group-3 (above 1.0 ng/mL). Among the PET-positive BCR patients (n = 26), local recurrence was detected in 57.7% (15/26), pelvic LN in 42.3% (11/26), and bone metastasis in 15.4% (4/26). In 53% (8/15) of BCR patients who were suspected of local recurrence, focal uptake was detected adjacent to the bladder on [

conclusions[

trial registration(UMIN Clinical Trials Registry) UMIN000037697.

Indexed as

AgedBone NeoplasmsDiagnostic ImagingHumansMaleMiddle AgedNeoplasm MetastasisNeoplasm Recurrence, LocalNiacinamideOligopeptidesPositron-Emission TomographyProstateProstatectomyProstatic NeoplasmsRadiopharmaceuticalsUrinary BladderNiacinamideOligopeptidesPSMA-1007RadiopharmaceuticalsBiochemical recurrenceDiagnosisPETProstate cancerPSMA

Identifiers

PMID33661475
PMCPMC7981319
OpenAlexW3135424945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.