ArticleEuropean journal of nutrition2021
Associations between maternal vitamin D status during three trimesters and cord blood 25(OH)D concentrations in newborns: a prospective Shanghai birth cohort study.
Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 6 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 6 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Associations of Prenatal Vitamin D status with Oral Health in Offspring: A Systematic Review.Oral health & preventive dentistry · 2022Pooled it
- Impact of surgical resection of butterfly glioblastoma on survival: a meta-analysis based on comparative studies.Scientific reports · 2021Pooled it
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- Genetic polymorphisms as prognostic factors for recurrent kidney stones: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Association of GSTP1 Ile105Val polymorphism with the risk of coronary heart disease: An updated meta-analysis.PloS one · 2021Pooled it
- Pooled it
- [Vitamin D level in umbilical cord blood of late preterm infants and the effect of vitamin DZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Trial
- Trial
- Incidence and clinical characteristics of pediatric vitamin D deficiency in Hokkaido, Japan: A survey of cases diagnosed between 2015 and 2019.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Article
- Associations of umbilical cord vitamin D levels with childhood cardiometabolic risks: a longitudinal mother-child study.Frontiers in nutrition · 2026Article
- Correlation between anthropometric and biological parameters of the offspring and parental plasma 25-hydroxyvitamin D levels: a cross-sectional study conducted at Oran, Algeria.BMC pregnancy and childbirth · 2025Article
- Vitamin D exerts endogenous control over TiScience · 2025Article
- Maternal Vitamin D Deficiency Is a Risk Factor for Infants' Epigenetic Gestational Age Acceleration at Birth in Japan: A Cohort Study.Nutrients · 2025Article
- Association of cord blood vitamin D and genetic polymorphisms with childhood food allergy in Shanghai, China: a prospective cohort.Frontiers in nutrition · 2025Article
- Associations between Longitudinal Maternal and Cord Blood Vitamin D Status and Child Growth Trajectories Up to 4 Years of Age.Nutrients · 2024Article
- Causal association of blood cell traits with inflammatory bowel diseases: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- Low levels of Vitamin D during pregnancy associated with gestational diabetes mellitus and low birth weight: results from the MAASTHI birth cohort.Frontiers in nutrition · 2024Article
- The Association of Prenatal Vitamin D Status With Pregnancy and Neonatal Outcomes.Journal of the Endocrine Society · 2023Article
- Maternal and neonatal blood vitamin D status and neurodevelopment at 24 months of age: a prospective birth cohort study.World journal of pediatrics : WJP · 2023Article
- Article
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Authors and funding
10 authors at 1 institution in 2 countries.
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Abstract
purposePrenatal vitamin D (VitD) deficiency influences children's health in later life. We aimed to test the associations between maternal VitD status in each of the three trimesters of pregnancy and cord blood 25(OH)D concentrations in newborns.
methodsParticipants were pregnant women recruited from the Shanghai Birth Cohort (SBC) (n = 1100). Of all the participants, 946 completed the collection of venous blood at early (< 16 weeks, T1), mid- (24-28 weeks, T2), and late (32-34 weeks, T3) pregnancy as well as the corresponding cord blood in the newborns. Maternal serum 25(OH)D concentrations were measured by LC-MS/MS, and the information on confounding factors was obtained through a standardized questionnaire.
resultsThe mean 25(OH)D concentrations at time points T1, T2, T3 in maternal blood and cord blood of the newborns were 26.31 ng/mL, 31.92 ng/mL, 35.62 ng/mL, and 19.77 ng/mL, respectively. Neonatal 25(OH)D level in cord blood was positively correlated with maternal serum 25(OH)D levels at each trimester, and the strongest correlation was found at time point T3.
conclusionMaternal 25(OH)D concentrations at each trimester were positively associated with neonatal VitD status in cord blood, and the strongest correlation was found in the late stage of pregnancy, which could be considered as a sensitive time window. Attention should be paid to the nutritional status of VitD during pregnancy to better prevent the VitD deficiency in neonates.
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