Evidence map›Paper›PMID 33661372›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2021

Impact of effective regurgitant orifice area on outcome of secondary mitral regurgitation transcatheter repair.

Nicole Karam, Mathias Orban, Daniel Kalbacher, Christian Butter, Fabien Praz, Edith Lubos, Marwin Bannehr, Mohammad Kassar, Aniela Petrescu, Christos Iliadis and 9 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Mitral valve transcatheter edge-to-edge repair.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nicole Karam *Department of Cardiology and Paris Cardiovascular Research Center (INSERM U970), European Hospital Georges Pompidou, Paris, France.
Mathias Orban *Medizinische Klinik und Poliklinik I, Ludwig Maximilians Universität München, Munich, Germany.
Daniel KalbacherKlinik für Kardiologie, UKE Hamburg, Universitäres Herz- und Gefäßzentrum, Hamburg, Germany.
Christian ButterDepartment of Cardiology, Heart Center Brandenburg and Brandenburg Medical School, Bernau, Germany.
Fabien PrazDepartment of Cardiology, University Hospital, University of Bern, Bern, Switzerland.
Edith LubosKlinik für Kardiologie, UKE Hamburg, Universitäres Herz- und Gefäßzentrum, Hamburg, Germany.
Marwin BannehrDepartment of Cardiology, Heart Center Brandenburg and Brandenburg Medical School, Bernau, Germany.
Mohammad KassarDepartment of Cardiology, University Hospital, University of Bern, Bern, Switzerland.
Aniela PetrescuMainz University Hospital, University of Mainz, Mainz, Germany.
Christos IliadisDepartment III of Internal Medicine, Heart Center, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Matthias UnterhuberDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Anouk AsselinDepartment of Cardiology and Paris Cardiovascular Research Center (INSERM U970), European Hospital Georges Pompidou, Paris, France.
Holger ThieleDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Roman PfisterDepartment III of Internal Medicine, Heart Center, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Stephan WindeckerDepartment of Cardiology, University Hospital, University of Bern, Bern, Switzerland.
Philipp LurzDepartment of Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany.
Stephan von BardelebenMainz University Hospital, University of Mainz, Mainz, Germany.
Jörg HausleiterMedizinische Klinik und Poliklinik I, Ludwig Maximilians Universität München, Munich, Germany. joerg.hausleiter@med.uni-muenchen.de.
EuroSMR investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the value of effective regurgitant orifice (ERO) in predicting outcome after edge-to-edge transcatheter mitral valve repair (TMVR) for secondary mitral regurgitation (SMR) and identify the optimal cut-off for patients' selection.

methodsUsing the EuroSMR (European Registry of Transcatheter Repair for Secondary Mitral Regurgitation) registry, that included patients undergoing edge-to-edge TMVR for SMR between November 2008 and January 2019 in 8 experienced European centres, we assessed the optimal ERO threshold associated with mortality in SMR patients undergoing TMVR, and compared characteristics and outcomes of patients according to baseline ERO.

resultsAmong 1062 patients with severe SMR and ERO quantification by proximal isovelocity surface area method in the registry, ERO was < 0.3 cm

conclusionAll-cause mortality at 2 years after TMVR does not differ if baseline ERO is < or ≥ 0.3 cm

Indexed as

Patient SelectionAgedAged, 80 and overCardiac CatheterizationCohort StudiesFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHumansMaleMitral Valve InsufficiencyMortalityPrognosisRegistriesRetrospective StudiesSeverity of Illness IndexEdge-to-edge repairEffective regurgitant orifice areaHeart failure with reduced ejection fractionMitral regurgitationOutcome

Identifiers

PMID33661372
PMCPMC8099828

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.