Evidence map›Paper›PMID 33661331›Full record

Observational studyRheumatology international2021

Increased influenza vaccination rates in patients with autoimmune rheumatic diseases during the Covid-19 pandemic: a cross-sectional study.

George E Fragoulis, Ioannis Grigoropoulos, Evgenia Mavrea, Aikaterini Arida, Vassiliki-Kalliopi Bournia, Gerasimos Evangelatos, Kalliopi Fragiadaki, Anastasios Karamanakos, Evrydiki Kravvariti, Stylianos Panopoulos and 6 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

George E FragoulisRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece. geofragoul@yahoo.gr.ORCID 0000-0003-4932-7023
Ioannis Grigoropoulos2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, Hippokration General Hospital, Athens, Greece.
Evgenia Mavrea2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, Hippokration General Hospital, Athens, Greece.
Aikaterini AridaRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0001-6085-1518
Vassiliki-Kalliopi BourniaRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0002-2162-1362
Gerasimos EvangelatosRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0003-3822-3093
Kalliopi FragiadakiRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.
Anastasios KaramanakosRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.
Evrydiki KravvaritiRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0003-4330-3266
Stylianos PanopoulosRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0002-3720-5996
Maria PappaRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.
Konstantinos Thomas2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, Hippokration General Hospital, Athens, Greece.ORCID 0000-0002-7489-7776
Maria G TektonidouRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0003-2238-0975
Dimitrios ParaskevisDepartment of Hygiene Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-6167-7152
Dimitrios Vassilopoulos2nd Department of Medicine and Laboratory, Clinical Immunology-Rheumatology Unit, Hippokration General Hospital, Athens, Greece.ORCID 0000-0003-2288-3863
Petros P SfikakisRheumatology Unit, First Department of Propaedeutic Internal Medicine, Joint Rheumatology Program, National and Kapodistrian University of Athens Medical School, Laiko General Hospital, MikrasAsias 75 Street, 11527, Athens, Greece.ORCID 0000-0001-5484-2930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess non-compliance and potential changes in seasonal flu vaccination coverage before and during the Covid-19 pandemic in patients with autoimmune rheumatic diseases (ARDs). Consecutive patients with ARDs followed-up in 2 tertiary hospitals were telephone-interviewed (December 12-30, 2020) regarding seasonal flu vaccination during the 2019/20 and 2020/21 time periods. Self-reported disease flares that occurred after flu vaccination, as well as reasons for non-vaccination were recorded. One thousand fifteen patients were included. The rate of flu vaccination increased from 76% before to 83% during the COVID-19 pandemic (p = 0.0001). The rate of self-reported disease flares was < 1% among vaccinated patients. Reasons for not vaccination in both periods, respectively, included: 'was not recommended by their rheumatologists' (35.0vs.12.2%, p < 0.0001), 'did not feel that they would have any benefit' (36.9 vs. 32.6%), felt unsafe to do so (27.5 vs. 30.2%), or other reasons (18.9 vs. 23.8%). By multivariate analysis, age [OR = 1.03 (95% CI 1.02-1.04)] vs. [1.04 (95% CI 1.02-1.05)] and treatment with biologics [OR = 1.66 (95% CI 1.22-2.24) vs. [1.68 (95% CI 1.19-2.38)] were independent factors associated with vaccination in both periods. These findings, although are temporally encouraging, emphasize the need for continuous campaigns aiming at increasing patients' and physicians' awareness about the benefits of vaccination.

Indexed as

AdultAgedAged, 80 and overAutoimmune DiseasesCOVID-19Cross-Sectional StudiesFemaleHumansInfluenza, HumanInfluenza VaccinesMaleMiddle AgedPandemicsPatient ComplianceRheumatic DiseasesSARS-CoV-2Influenza VaccinesAutoimmune rheumatic diseasesCovid-19InfluenzaVaccination

Identifiers

PMID33661331
PMCPMC7931496

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.