Evidence map›Paper›PMID 33661093›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2021

Canadian Urological Association best practice report: Prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) and PET/magnetic resonance (MR) in prostate cancer.

Bobby Shaygan, Katherine Zukotynski, François Bénard, Cynthia Ménard, Joda Kuk, Golmehr Sistani, Glenn Bauman, Patrick Veit-Haibach, Ur Metser

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Gender bias in shared decision-making among cancer care guidelines: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2023
    Pooled it
  2. Pooled it
  3. Case - Radiation-induced sarcoma A pitfall during PSMA-targeted radioligand therapy.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Standardized template for clinical reporting of PSMA PET/CT scans.European journal of nuclear medicine and molecular imaging · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  13. On the Way for Patients with Prostate Cancer to the Best Use of PSMA.International journal of molecular sciences · 2022
    Article
  14. PSMA PET in Imaging Prostate Cancer.Frontiers in oncology · 2022
    Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Bobby ShayganDepartment of Urology, McMaster University, Hamilton, ON, Canada.
Katherine ZukotynskiDepartments of Medicine and Radiology, McMaster University, Hamilton, ON, Canada.
François BénardPET Functional Imaging, BC Cancer, Vancouver, BC, Canada.
Cynthia MénardDepartment of Radiation Oncology, Université de Montréal, Montreal, QC, Canada.
Joda KukGrand River Regional Cancer Centre, Grand River Hospital, Kitchener, ON, Canada.
Golmehr SistaniDepartment of Medical Imaging, Western University, London, ON, Canada.
Glenn BaumanDepartment of Oncology, Western University, London, ON, Canada.
Patrick Veit-HaibachJoint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Ur MetserJoint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
McMaster University · CAUniversity of Toronto · CAWestern University · CASpinal Cord Injury BC · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) is increasingly being used worldwide as part of the clinical workup for men with prostate cancer. With high overall accuracy for the detection of prostate cancer, PSMA-targeted PET has an increasingly established role in the setting of biochemical failure after primary therapy and an evolving role in the setting of initial disease staging; its utility for guiding management in the setting of metastatic disease is less clear. Although the specificity is high, familiarization with potential pitfalls in the interpretation of PSMA-targeted PET, including knowledge of the causes for false-positive and negative examinations, is critical. The aim of this best practice report is to provide an illustrative discussion of the current and evolving clinical indications for PSMA-targeted PET, as well as a review of physiological radiopharmaceutical biodistribution and potential imaging pitfalls.

Identifiers

PMID33661093
PMCPMC8195587
OpenAlexW3134481849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.