ArticleCroatian medical journal2021
Salivary cortisol response to psychosocial stress in patients with first-episode psychosis.
Article in Croatian medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- How physical multimorbidity affected the mental health and healthcare utilization of patients with severe mental illness during the COVID-19 pandemic and earthquakes.Frontiers in psychiatry · 2025Article
- Cortisol response to psychosocial stress, mental distress, fatigue and quality of life in coronary artery disease patients.Scientific reports · 2022Article
- Psychotropic Drug Effects on Steroid Stress Hormone Release and Possible Mechanisms Involved.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo analyze the difference in the salivary cortisol response to psychosocial stress between the patients with the first episode of psychosis (FEP) and the control group.
methodsWe performed a cross-sectional analysis of the baseline measurements of a prospective cohort study conducted from 2015 to 2018 at two Croatian psychiatric hospitals. The study consecutively enrolled 53 patients diagnosed with FEP and 63 healthy controls. The primary outcome was the difference in the changes of salivary cortisol concentration during the stress test. The secondary outcome was the difference in the baseline levels of salivary cortisol between patients with FEP and controls. The tertiary outcome were the correlations of salivary cortisol levels with the results of the Positive and Negative Syndrome Scale for Schizophrenia, Rosenberg Self-Esteem Scale, and the International Personality Item Pool.
resultsPatients with FEP had significantly higher baseline salivary cortisol than controls, but their salivary cortisol increased significantly less during the stress test.
conclusionPatients with FEP respond differently to stressful stimuli than controls, as shown by the increased baseline salivary cortisol and blunted cortisol response, possibly indicating a greater vulnerability to psychosocial stress.
Indexed as
Identifiers
33660964PMC7976886W3134181549What OpenQuestion holds
Registered trials
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