Evidence map›Paper›PMID 33660906›Full record

Trial reportEuropean eating disorders review : the journal of the Eating Disorders Association2021

Treatment outcomes of psychotherapy for binge-eating disorder in a randomized controlled trial: Examining the roles of childhood abuse and post-traumatic stress disorder.

Vivienne M Hazzard, Ross D Crosby, Scott J Crow, Scott G Engel, Lauren M Schaefer, Timothy D Brewerton, Giovanni Castellini, Kathryn Trottier, Carol B Peterson, Stephen A Wonderlich

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European eating disorders review : the journal of the Eating Disorders Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Therapists' Attitudes and Exclusion Criteria for Prolonged Exposure and EMDR in Patients With Eating Disorders and PTSD.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Binge eating disorder.Nature reviews. Disease primers · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Vivienne M HazzardSanford Center for Biobehavioral Research, Fargo, North Dakota, USA.ORCID 0000-0003-3933-1766
Ross D CrosbySanford Center for Biobehavioral Research, Fargo, North Dakota, USA.
Scott J CrowDepartment of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Scott G EngelSanford Center for Biobehavioral Research, Fargo, North Dakota, USA.
Lauren M SchaeferSanford Center for Biobehavioral Research, Fargo, North Dakota, USA.
Timothy D BrewertonDepartment of Psychiatry & Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0001-9655-3600
Giovanni CastelliniDepartment of Health Sciences, Psychiatry Unit, University of Florence, Florence, Italy.ORCID 0000-0003-1265-491X
Kathryn TrottierDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7192-6140
Carol B PetersonDepartment of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Stephen A WonderlichSanford Center for Biobehavioral Research, Fargo, North Dakota, USA.
Sanford Research · USUniversity of Minnesota Medical Center · USUniversity of North Dakota · USMedical University of South Carolina · USUniversity of Florence · ITUniversity of Toronto · CA

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI CROW, SCOTT J · 1995 to 2015
$17.0M
Regional Postdoctoral Training Grant in Eating Disorders ResearchT32MH082761 · NIMH · UNIVERSITY OF MINNESOTA · PI CAROL B. PETERSON · 2009 to 2026
$6.2M
Integrative Cognitive Affective Therapy for Binge Eating DisorderR34MH098995 · NIMH · SANFORD RESEARCH NORTH · PI WONDERLICH, STEPHEN ARTHUR · 2013 to 2015
$696k
1/2-Integrative Cognitive Affective Therapy for Binge Eating DisorderR34MH099040 · NIMH · UNIVERSITY OF MINNESOTA · PI PETERSON, CAROL B. · 2013 to 2015
$684k
NIDDK NIH HHS P30 DK050456NIMH NIH HHS R34 MH098995NIMH NIH HHS R34 MH099040NIMH NIH HHS T32 MH082761
6 · The paper itself

Abstract

objectiveTo examine childhood abuse and post-traumatic stress disorder (PTSD) as predictors and moderators of binge-eating disorder (BED) treatment outcomes in a randomized controlled trial comparing Integrative Cognitive-Affective Therapy with cognitive-behavioural therapy administered using guided self-help.

methodIn 112 adults with BED, childhood abuse was defined as any moderate/severe abuse as assessed by the Childhood Trauma Questionnaire, lifetime PTSD was assessed via the Structured Clinical Interview for DSM-IV, and outcomes were assessed via the Eating Disorder Examination (EDE). Covariate-adjusted regression models predicting binge-eating frequency and EDE global scores at end of treatment and 6-month follow-up were conducted.

resultsLifetime PTSD predicted greater binge-eating frequency at end of treatment (B = 1.32, p = 0.009) and childhood abuse predicted greater binge-eating frequency at follow-up (B = 1.00, p = 0.001). Lifetime PTSD moderated the association between childhood abuse and binge-eating frequency at follow-up (B = 2.98, p = 0.009), such that childhood abuse predicted greater binge-eating frequency among participants with a history of PTSD (B = 3.30, p = 0.001) but not among those without a PTSD history (B = 0.31, p = 0.42). No associations with EDE global scores or interactions with treatment group were observed.

conclusionsResults suggest that a traumatic event history may hinder treatment success and that PTSD may be more influential than the trauma exposure itself.

Indexed as

Binge-Eating DisorderChild AbuseStress Disorders, Post-TraumaticAdultChildHumansPsychotherapyTreatment Outcomebinge-eating disorderchildhood abuseeating disorderspost-traumatic stress disorderpsychotherapy

Identifiers

PMID33660906
PMCPMC8187312
OpenAlexW3135843262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.