Evidence map›Paper›PMID 33660524›Full record

ArticleJournal of the American Heart Association2021

Prediction of Death After Noncardiac Surgery: Potential Advantage of Using High-Sensitivity Troponin T as a Continuous Variable.

Mauricio N Machado, Fernando B Rodrigues, Marcelo A Nakazone, Danilo F Martin, Amália T R Sabbag, Ingrid H Grigolo, Osvaldo L Silva-Júnior, Lilia N Maia, Allan S Jaffe

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Mauricio N MachadoDivision of Cardiology Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Fernando B RodriguesDivision of Emergency and Chest Pain Center Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Marcelo A NakazoneDivision of Cardiology Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Danilo F MartinDivision of Cardiology Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Amália T R SabbagDivision of Anesthesiology Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Ingrid H GrigoloIntegrated Research Center Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Osvaldo L Silva-JúniorIntegrated Research Center Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Lilia N MaiaDivision of Cardiology Hospital de Base Faculdade de Medicina de São José do Rio Preto São Paulo Brazil.
Allan S JaffeCardiovascular Department and Department of Laboratory Medicine and Pathology Mayo Clinic MN.
Faculdade de Medicina de São José do Rio Preto · BRMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Increased high-sensitivity cardiac troponin T (hs-cTnT) above the upper reference limit (URL) after noncardiac surgery identifies patients at risk for mortality. Prior studies have not analyzed hs-cTnT as a continuous variable or probed age- and sex-specific URLs. This study compared the prediction of 30-day mortality using continuous postoperative hs-cTnT levels to the use of the overall URL and age- and sex-specific URLs. Methods and Results Patients (876) >40 years of age who underwent noncardiac surgery were included. Hs-cTnT was measured on postoperative day 1. Cox proportional hazards models were used to compare associations between 30-day mortality and using hs-cTnT as a continuous variable, or above the overall or age- and sex-specific URLs. Comparisons were performed by the area under the receiver operating characteristic curve analysis. Mortality was 4.2%. For each 1 ng/L increase in postoperative hs-cTnT, there was a 0.3% increase in mortality (

Indexed as

AdultAgedBiomarkersBrazilCardiovascular DiseasesFemaleHumansIncidenceMaleMiddle AgedPostoperative PeriodRisk AssessmentROC CurveSurgical Procedures, OperativeSurvival RateTroponin TBiomarkersTroponin Tnoncardiac surgeryprognosistroponin

Identifiers

PMID33660524
PMCPMC8174224
OpenAlexW3133971823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.