Evidence map›Paper›PMID 33660520›Full record

ArticleJournal of the American Heart Association2021

Manifestations and Outcome of Cardiac Sarcoidosis and Idiopathic Giant Cell Myocarditis by 25-Year Nationwide Cohorts.

Hanna-Kaisa Nordenswan, Jukka Lehtonen, Kaj Ekström, Anne Räisänen-Sokolowski, Mikko I Mäyränpää, Tapani Vihinen, Heikki Miettinen, Kari Kaikkonen, Petri Haataja, Tuomas Kerola and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Incidence and predictors of major arrhythmic events after myocarditis: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
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  4. Review
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  6. Article
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  12. A fearsome evolution of presumed cardiac sarcoidosis: The sarcoid-lymphoma syndrome.International journal of cardiology. Heart & vasculature · 2024
    Article
  13. Review
  14. Article
  15. Review
  16. Cardiac Sarcoidosis: A Comprehensive Clinical Review.Reviews in cardiovascular medicine · 2024
    Review
  17. Sarcoid heart disease and imaging.Heart rhythm O2 · 2024
    Review
  18. Life threating onset of Cardiac Sarcoidosis with mediastinal involvement.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2023
    Article
  19. Review
  20. High-risk and low prevalence disease: Cardiac sarcoidosis and some of its mimics.International journal of cardiology. Heart & vasculature · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Hanna-Kaisa NordenswanHeart and Lung Center University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
Jukka LehtonenHeart and Lung Center University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
Kaj EkströmHeart and Lung Center University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
Anne Räisänen-SokolowskiDepartment of Pathology University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
Mikko I MäyränpääDepartment of Pathology University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
Tapani VihinenHeart Center Turku University Hospital Turku Finland.
Heikki MiettinenHeart Center Kuopio University Hospital Kuopio Finland.
Kari KaikkonenMedical Research Center Oulu University and University Hospital of Oulu Oulu Finland.
Petri HaatajaHeart HospitalTampere University Hospital Tampere Finland.
Tuomas KerolaDepartment of Internal Medicine Päijät-Häme Central Hospital Lahti Finland.
Tuomas T RissanenHeart Center North Karelia Central Hospital Joensuu Finland.
Jorma KokkonenCentral Finland Central Hospital Jyväskylä Finland.
Aleksi AlataloSouth Ostrobothnia Central Hospital Seinäjoki Finland.
Päivi Pietilä-EffatiVaasa Central Hospital Vaasa Finland.
Seppo UtriainenSouth Karelia Central Hospital Lappeenranta Finland.
Markku KupariHeart and Lung Center University of Helsinki and Helsinki University Central Hospital Helsinki Finland.
University of Helsinki · FICentral Finland Health Care District · FIKuopio University Hospital · FINorth Karelia Central Hospital · FIOulu University Hospital · FIPäijät-Hämeen Keskussairaala · FISeinäjoki University of Applied Sciences · FISouth Karelia Central Hospital · FITampere University Hospital · FITurku University Hospital · FIVaasa Central Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cardiac sarcoidosis (CS) and giant cell myocarditis (GCM) share many histopathologic and clinical features. Whether they are parts of a one-disease continuum has been discussed. Methods and Results We compared medical record data of 351 CS and 28 GCM cases diagnosed in Finland since the late 1980s and followed until February 2018 for a composite end point of cardiac death, aborted sudden death, and heart transplantation. Heart failure was the presenting manifestation in 50% versus 15% (

Indexed as

ForecastingPopulation SurveillanceAdultAgedBiomarkersCardiomyopathiesCause of DeathFemaleFollow-Up StudiesGiant CellsHumansIncidenceMaleMiddle AgedMyocardiumNatriuretic Peptide, BrainBiomarkersNatriuretic Peptide, Braincardiac sarcoidosisgiant cell myocarditisinflammatory heart disease

Identifiers

PMID33660520
PMCPMC8174201
OpenAlexW3134828210

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.