ArticleKorean journal of radiology2021
Malignancy Risk Stratification of Thyroid Nodules with Macrocalcification and Rim Calcification Based on Ultrasound Patterns.
Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04904159 (A New Scoring System in the Diagnosis of Thyroid Gland Pathologies), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A New Scoring System in the Diagnosis of Thyroid Gland Pathologies
Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Determining malignancy in thyroid nodules featuring anterior macrocalcifications with strong posterior acoustic shadowing: the combined utility of US-FNA andQuantitative imaging in medicine and surgery · 2026Article
- Precision medicine in thyroid nodules: current strategies, challenges, and future directions.Hormones (Athens, Greece) · 2026Review
- Advantages of thyroid core needle biopsy: an emerging selective first-line biopsy modality.Ultrasonography (Seoul, Korea) · 2026Article
- Nomogram for predicting papillary thyroid carcinoma risk combined with clinical, biochemical and ultrasonographic indicators.BMC cancer · 2026Article
- Independent predictors and ultrasound-based risk stratification for follicular thyroid tumors: a multicenter retrospective study.World journal of surgical oncology · 2025Article
- Preoperative multiparametric ultrasound for the prediction of central lymph node metastasis in papillary thyroid carcinoma.Quantitative imaging in medicine and surgery · 2025Article
- Correlation between ultrasound calcification patterns, and clinicopathological factors and recurrence risk in papillary thyroid carcinoma.Gland surgery · 2025Article
- The effect of thyroid nodule location in ultrasound on the diagnosis of papillary thyroid carcinoma.Discover oncology · 2025Article
- Article
- The value of non-punctate echogenic foci in the ultrasonic diagnosis of thyroid nodules.Endocrine · 2025Article
- Malignancy risk stratification and subcategorization of K-TIRADS intermediate suspicion thyroid nodules: a retrospective multicenter study.Ultrasonography (Seoul, Korea) · 2024Article
- A novel approach to quantify calcifications of thyroid nodules in US images based on deep learning: predicting the risk of cervical lymph node metastasis in papillary thyroid cancer patients.European radiology · 2023Article
- Deep learning approaches for differentiating thyroid nodules with calcification: a two-center study.BMC cancer · 2023Article
- How to Clearly and Accurately Report Odds Ratio and Hazard Ratio in Diagnostic Research Studies?Korean journal of radiology · 2022Article
- Clinicoradiological Characteristics in the Differential Diagnosis of Follicular-Patterned Lesions of the Thyroid: A Multicenter Cohort Study.Korean journal of radiology · 2022Article
- Introducing a Pole Concept for Nodule Growth in the Thyroid Gland: Taller-than-Wide Shape, Frequency, Location and Risk of Malignancy of Thyroid Nodules in an Area with Iodine Deficiency.Journal of clinical medicine · 2022Article
- Prophylactic central lymph node dissection performed selectively with cN0 papillary thyroid carcinoma according to a risk-scoring model.Gland surgery · 2022Article
- Role of echogenic foci in ultrasonographic risk stratification of thyroid nodules: Echogenic focus scoring in the American College of Radiology Thyroid Imaging Reporting and Data System.Frontiers in oncology · 2022Article
- 2021 Korean Thyroid Imaging Reporting and Data System and Imaging-Based Management of Thyroid Nodules: Korean Society of Thyroid Radiology Consensus Statement and Recommendations.Korean journal of radiology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo determine the association of macrocalcification and rim calcification with malignancy and to stratify the malignancy risk of thyroid nodules with macrocalcification and rim calcification based on ultrasound (US) patterns. MATERIALS AND
methodsThe study included a total of 3603 consecutive nodules (≥ 1 cm) with final diagnoses. The associations of macrocalcification and rim calcification with malignancy and malignancy risk of the nodules were assessed overall and in subgroups based on the US patterns of the nodules. The malignancy risk of the thyroid nodules was categorized as high (> 50%), intermediate (upper-intermediate: > 30%, ≤ 50%; lower-intermediate: > 10%, ≤ 30%), and low (≤ 10%).
resultsMacrocalcification was independently associated with malignancy in all nodules and solid hypoechoic (SH) nodules (
conclusionMacrocalcification increased the malignancy risk in all and SH nodules with or without suspicious US features, with low to high malignancy risks depending on the US patterns. Rim calcification increased the malignancy risk in PCIH nodules, with low and lower-intermediate malignancy risks based on suspicious US features. However, the role of rim calcification in risk stratification of thyroid nodules remains uncertain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.