Evidence map›Paper›PMID 33660225›Full record

ArticleJournal of gastrointestinal cancer2022

Impact of BMI on Adverse Events After Laparoscopic and Open Surgery for Rectal Cancer.

Dhruvin H Hirpara, Colin O'Rourke, Arash Azin, Fayez A Quereshy, Steven D Wexner, Sami A Chadi

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dhruvin H HirparaDepartment of Surgery, University of Toronto, 149 College St., ON, M5T1P5, Toronto, USA.
Colin O'RourkeBenaroya Research Institute, Virginia Mason, 1201 Ninth Ave., WA, 98101-2795, Seattle, USA.
Arash AzinDepartment of Surgery, University of Toronto, 149 College St., ON, M5T1P5, Toronto, USA.
Fayez A QuereshyDivision of Surgical Oncology and General Surgery, University Health Network and Princess Margaret Hospital, 399 Bathurst St., ON, M5T2S8, Toronto, USA.
Steven D WexnerDepartment of Colorectal Surgery, Digestive Disease Centre, Cleveland Clinic Florida, Cleveland Clinic Blvd., FL, Weston, USA.
Sami A ChadiDivision of Surgical Oncology and General Surgery, University Health Network and Princess Margaret Hospital, 399 Bathurst St., ON, M5T2S8, Toronto, USA. sami.chadi@uhn.ca.
Health Net · USBenaroya Research InstituteCleveland Clinic Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe impact of body mass index (BMI) on outcomes after open or laparoscopic surgery for rectal cancer remains unclear. The objective of this retrospective cohort study was to examine the interaction of body mass index and surgical modality (i.e., laparoscopy versus open) with respect to short-term clinical outcomes in patients with rectal cancer.

methodsThe ACS-NSQIP database (2012-2016) was reviewed for patients undergoing open or laparoscopic surgery for rectal cancer. The primary outcome was 30-day all-cause morbidity. Logistic regression and Cox proportional hazard models were used for analysis.

resultsA total of 16,145 patients were grouped into open (N = 6759, 42%) and laparoscopic (N  = 9386, 58%) cohorts. Patients with higher BMI (p < 0.001) and those undergoing open surgery (p < 0.001) were at increased risk of all-cause morbidity. There was no significant change in the odds ratio of experiencing all-cause morbidity between open and laparoscopic surgery with increasing BMI (p = 0.572). Median length of stay was significantly shorter in the laparoscopy group (4 days vs. 6 days; p < 0.001), at the cost of increased operative time (239 min vs. 210 min, p < 0.001). The difference in operative time between laparoscopy and open surgery did not increase with rising BMI (i.e., ∆37 min vs. ∆39 min at BMI 25 kg/m

conclusionBMI may not be a strong modifier for surgical approach with respect to short-term clinical outcomes in patients with obesity and rectal cancer. Laparoscopic surgery was associated with improved short-term clinical outcomes, without much change in the absolute difference in operative time compared with open surgery, even at higher BMIs.

Indexed as

LaparoscopyRectal NeoplasmsBody Mass IndexHumansPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAdverse eventsBody mass indexLaparoscopyLaparotomyRectal cancer

Identifiers

PMID33660225
OpenAlexW3134927510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.