Evidence map›Paper›PMID 33660080›Full record

Trial reportPsychopharmacology2021

Acute alcohol does not impair attentional inhibition as measured with Stroop interference scores but impairs Stroop performance.

P Riedel, M Wolff, M Spreer, J Petzold, M H Plawecki, T Goschke, U S Zimmermann, M N Smolka

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

P RiedelDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M WolffDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M SpreerDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
J PetzoldDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M H PlaweckiDepartment of Psychiatry, Indiana University School of Medicine, 355 West 16th Street, Indianapolis, IN, 46202, USA.
T GoschkeNeuroimaging Center, Technische Universität Dresden, Würzburger Straße 35, 01187, Dresden, Germany.
U S ZimmermannDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
M N SmolkaDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany. michael.smolka@tu-dresden.de.ORCID http://orcid.org/0000-0001-5398-5569
Technische Universität Dresden · DEIndiana University School of MedicineIsar-Amper-Klinikum München-Ost · DEKlinik und Poliklinik für Psychotherapie und Psychosomatik · DE

Funding

Translational Research and Science Education (OUT)P60AA007611 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Nicholas Joseph Grahame · 2003 to 2026
$45.5M
NIAAA NIH HHS P60 AA007611NIAAA NIH HHS P60AA07611
6 · The paper itself

Abstract

rationaleInhibition is a core executive function and refers to the ability to deliberately suppress attention, behavior, thoughts, and/or emotions and instead act in a specific manner. While acute alcohol exposure has been shown to impair response inhibition in the stop-signal and Go/NoGo tasks, reported alcohol effects on attentional inhibition in the Stroop task are inconsistent. Notably, studies have operationalized attentional inhibition variably and there has been intra- and inter-individual variability in alcohol exposure.

objectiveThis study aimed to examine the acute effects of alcohol on attentional inhibition, considering previous limitations.

methodsIn a single-blind, cross-over design, 40 non-dependent participants with a medium-to-high risk drinking behavior performed a Counting Stroop task (CST) under a baseline and an arterial blood alcohol concentration (aBAC) clamp at 80 mg%. Attentional inhibition was assessed as the alteration of reaction times (RT), error rates (ER), and inverse efficiency scores (IES) between incongruent and congruent trials (interference score). Stroop performance was also assessed regardless of trial-type.

resultsCompared to saline, acute alcohol exposure via an aBAC clamp did not affect CST interference scores but increased RTs and IES in both incongruent and congruent trials.

conclusionsAttentional inhibition (Stroop interference score) was not impaired by clamped moderate alcohol exposure. Acute alcohol impaired Stroop performance evidenced by a general increase in response times. Our findings suggest that response and attentional inhibition do not share the same neurocognitive mechanisms and are affected differently by alcohol. Results could also be explained by automated behaviors known to be relatively unaffected by acute alcohol.

Indexed as

Inhibition, PsychologicalAdultAlcohol DrinkingAttentionBlood Alcohol ContentCross-Over StudiesEthanolExecutive FunctionFemaleHumansMaleMiddle AgedReaction TimeSingle-Blind MethodStroop TestBlood Alcohol ContentEthanolAcute alcohol exposureAlcohol clamp methodInterference controlResponse inhibitionStroop task

Identifiers

PMID33660080
PMCPMC8139883
OpenAlexW3135686079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.