Evidence map›Paper›PMID 33659922›Full record

ReviewFaculty reviews2021

The cancer cell secretome drives cooperative manipulation of the tumour microenvironment to accelerate tumourigenesis.

Shona Ritchie, Daniel A Reed, Brooke A Pereira, Paul Timpson

Open access · diamondAbstract readReview
In one paragraph

Review in Faculty reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Emerging Roles of Cytoneme-Mediated Signaling in Cancer.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Tumor secretome shapes the immune landscape during cancer progression.Journal of experimental & clinical cancer research : CR · 2025
    Review
  11. Review
  12. Targeting the secretory program of 3q-amplified lung cancers.The Journal of clinical investigation · 2024
    Article
  13. Review
  14. Review
  15. Circulating Proteins as Diagnostic Markers in Gastric Cancer.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shona RitchieThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.
Daniel A ReedThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.
Brooke A PereiraThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.
Paul TimpsonThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.
St Vincent's Clinic · AUGarvan Institute of Medical Research · AUThe Kinghorn Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular secretions are a fundamental aspect of cell-cell and cell-matrix interactions

Indexed as

Cancer cell secretomePre-metastatic nicheStromaTumour microenvironment

Identifiers

PMID33659922
PMCPMC7894270
OpenAlexW3123954479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.