Evidence map›Paper›PMID 33659579›Full record

ArticleNeurobiology of stress2021

Cortical gyrification morphology in PTSD: A neurobiological risk factor for severity?

Avideh Gharehgazlou, J Don Richardson, Rakesh Jetly, Benjamin T Dunkley

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of stress, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Sensory alterations in post-traumatic stress disorder.Current opinion in neurobiology · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Avideh GharehgazlouNeurosciences & Mental Health, The Hospital for Sick Children (SickKids) Research Institute, Toronto, Ontario, Canada.
J Don RichardsonThe MacDonald Franklin OSI Research Centre, Lawson Health Research Institute, London, Ontario, Canada.
Rakesh JetlyCanadian Forces Health Services Group HQ, Department of National Defence, Ottawa, Ontario, Canada.
Benjamin T DunkleyNeurosciences & Mental Health, The Hospital for Sick Children (SickKids) Research Institute, Toronto, Ontario, Canada.
University of Toronto · CADepartment of National Defence · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-traumatic stress disorder (PTSD) is a prevalent psychiatric disorder, particularly among military personnel and veterans. Cortical gyrification, as a specific metric derived from structural MRI, is an index of the convoluted folding and patterning of the gyri and sulci, and is thought to facilitate the efficiency of local neuronal wiring. It has the potential to act as a neurobiological risk factor for emergent psychiatric disorders - to date, it has been understudied in PTSD. Here, using a local measure of the degree of gyrification (local Gyrification Index,

Indexed as

Cortical gyrificationlGIMilitaryPost-traumatic stress disorderStructural MRI

Identifiers

PMID33659579
PMCPMC7890044
OpenAlexW3125607774

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.