Evidence map›Paper›PMID 33659493›Full record

ArticleBio-protocol2020

Protocol for Isolation, Stimulation and Functional Profiling of Primary and iPSC-derived Human NK Cells.

Janine E Melsen, Maria Themeli, Monique M van Ostaijen-Ten Dam, Els van Beelen, Gertjan Lugthart, Rob C Hoeben, Marco W Schilham, Harald M Mikkers

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. CITEMORNA biology · 2022
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Janine E MelsenDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Maria ThemeliDepartment of Hematology, Amsterdam UMC, Amsterdam, The Netherlands.
Monique M van Ostaijen-Ten DamDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Els van BeelenDepartment of Immunohematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Gertjan LugthartDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Rob C HoebenDepartment of Cell & Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Marco W SchilhamDepartment of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
Harald M MikkersDepartment of Cell & Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Leiden University Medical Center · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are innate immune cells, characterized by their cytotoxic capacity, and chemokine and cytokine secretion upon activation. Human NK cells are identified by CD56 expression. Circulating NK cells can be further subdivided into the CD56

Indexed as

CD56ChemokinesCytokinesInduced pluripotent stem cellsLuminexNatural killer cellsPeripheral blood

Identifiers

PMID33659493
PMCPMC7842530
OpenAlexW3108445562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.