Evidence map›Paper›PMID 33659346›Full record

ArticleBio-protocol2020

Marina Franceschetti, Mark J Banfield, Clare E M Stevenson, Juan Carlos De La Concepcion

Abstract read
In one paragraph

Article in Bio-protocol, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marina FranceschettiDepartment of Biological Chemistry, John Innes Centre, Colney Lane, Norwich, NR4 7UH, UK.
Mark J BanfieldDepartment of Biological Chemistry, John Innes Centre, Colney Lane, Norwich, NR4 7UH, UK.
Clare E M StevensonDepartment of Biological Chemistry, John Innes Centre, Colney Lane, Norwich, NR4 7UH, UK.
Juan Carlos De La ConcepcionDepartment of Biological Chemistry, John Innes Centre, Colney Lane, Norwich, NR4 7UH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms of virulence and immunity are often governed by molecular interactions between pathogens and host proteins. The study of these interactions has major implications on understanding virulence activities, and how the host immune system recognizes the presence of pathogens to initiate an immune response. Frequently, the association between pathogen molecules and host proteins are assessed using qualitative techniques. As small differences in binding affinity can have a major biological effect,

Indexed as

AffinityBindingEffectorsKineticsNLRPathogensProtein-Protein interactionsSurface Plasmon Resonance

Identifiers

PMID33659346
PMCPMC7842709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.