Evidence map›Paper›PMID 33659283›Full record

ReviewFrontiers in cardiovascular medicine2021

Effects of Therapeutic Hypothermia on Normal and Ischemic Heart.

Kelly P Yamada, Taro Kariya, Tadao Aikawa, Kiyotake Ishikawa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kelly P YamadaCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Taro KariyaCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Tadao AikawaCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Kiyotake IshikawaCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Icahn School of Medicine at Mount Sinai · US

Funding

Percutaneous Left Ventricular Unloading for Cardiogenic Shock: Beyond Acute Hemodynamic SupportR01HL139963 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kiyotake Ishikawa · 2018 to 2026
$4.9M
NHLBI NIH HHS R01 HL139963
6 · The paper itself

Abstract

Therapeutic hypothermia has been used for treating brain injury after out-of-hospital cardiac arrest. Its potential benefit on minimizing myocardial ischemic injury has been explored, but clinical evidence has yet to confirm positive results in preclinical studies. Importantly, therapeutic hypothermia for myocardial infarction is unique in that it can be initiated prior to reperfusion, in contrast to its application for brain injury in resuscitated cardiac arrest patients. Recent advance in cooling technology allows more rapid cooling of the heart than ever and new clinical trials are designed to examine the efficacy of rapid therapeutic hypothermia for myocardial infarction. In this review, we summarize current knowledge regarding the effect of hypothermia on normal and ischemic hearts and discuss issues to be solved in order to realize its clinical application for treating acute myocardial infarction.

Indexed as

cardiac functionclinical trialendovascularhypothermiainfarct sizemyocardial infarctionphysiologypreclinical

Identifiers

PMID33659283
PMCPMC7919696
OpenAlexW3131882959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.