ArticleFrontiers in oncology2020
Survival Status of Esophageal Cancer Patients and its Determinants in Ethiopia: A Facility Based Retrospective Cohort Study.
Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 15 citations in OpenAlex.
- Early esophageal cancer diagnosis in Central Oromia, Ethiopia: patient and provider perspectives on barriers and facilitators.Scientific reports · 2026Article
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- Treatment Response in Advanced and Metastatic Esophageal Cancer Patients on Palliative Treatments in Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia: A Retrospective Study.Research square · 2026Article
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- Spatial clustering of esophageal cancer in central Oromia, Ethiopia: A spatial autocorrelation and scan statistics analysis.PloS one · 2026Article
- Esophageal cancer surgery in Ethiopia: postoperative mortality and long-term survival.Surgery in practice and science · 2025Article
- Lived experiences of dysphagia-related quality of life among esophageal cancer patients: a qualitative study.Health and quality of life outcomes · 2025Article
- Multiple mycotoxin exposure assessment through human biomonitoring in an esophageal cancer case-control study in the Arsi-Bale districts of Oromia region of Ethiopia.International journal of hygiene and environmental health · 2025Article
- Exploring Oesophageal Cancer in Ethiopia: Elevated Incidence in Females and Younger Cases.Cancer reports (Hoboken, N.J.) · 2024Article
- Landscape of esophageal cancer in Northern Kenya: experience from Garissa Regional Cancer Center.Ecancermedicalscience · 2024Article
- Survival After Diagnosis of Esophageal Squamous Cell Carcinoma in Malawi.JCO global oncology · 2023Article
- Determinants of survival outcomes among esophageal cancer patients at a national referral hospital in Kenya.Chronic diseases and translational medicine · 2023Article
- Esophageal and Head and Neck Cancer Patients Attending Ocean Road Cancer Institute in Tanzania from 2019 to 2021: An Observational Study.International journal of environmental research and public health · 2023Observational
- Clinicopathological characteristics and treatment outcomes of oesophageal cancer patients in Uganda.Ecancermedicalscience · 2023Article
- Burden of Cancer and Utilization of Local Surgical Treatment Services in Rural Hospitals of Ethiopia: A Retrospective Assessment from 2014 to 2019.The oncologist · 2022Article
- Data on histological characteristics, survival patterns and determinants of mortality among colorectal, esophageal and prostate cancer patients in Ethiopia.Data in brief · 2021Article
- Spatiotemporal Distribution, Time to Treatment Outcome Clustering and Determinants of Esophageal Cancer in Ethiopia, a Scoping Study.Cancer control : journal of the Moffitt Cancer CenterArticle
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3 authors at 2 institutions in 2 countries.
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Abstract
backgroundGlobally, the incidence and mortality due to esophageal cancer are increasing, particularly in low- and middle-income countries. Cancer of the esophagus is the eighth in incidence and seventh in cancer mortality in Ethiopia. A few studies have shown an increasing burden, however, little is known about the survival pattern and its determinants among esophageal cancer patients in Ethiopia. Therefore, we assessed the survival pattern and its determinants among esophageal cancer patients.
methodsWe conducted a retrospective cohort study among 349 esophageal cancer patients who were diagnosed at or referred to Tikur Anbessa Specialized Hospital, Ethiopia from January 2010 to May 2017. Using an abstraction form, nurses who were working at the oncology department extracted the data from patient charts. To estimate and compare the probability of survival among covariate categories, we performed a Kaplan-Meier survival analysis with the log-rank test. To identify the prognostic determinants of survival, we performed a multivariable Cox proportional regression analysis.
resultsThe median follow-up time was 32 months with interquartile range of 15 to 42. Overall, the median survival time after diagnosis with esophageal cancer was 4 months with one-, two- and three-year survival of 14.4, 6.3, and 2.4% respectively. In the multivariable Cox proportional hazards model, receiving chemotherapy [Adjusted Hazard Ratio (AHR)=0.36, 95%CI: 0.27-0.49], radiotherapy [AHR=0.38, 95%CI: 0.23-0.63] and surgery [AHR=0.70, 95%CI: 0.54-0.89] were statistically significant.
conclusionsIn Ethiopia, esophageal cancer patients have a very low one-, two- and three-year survival. Despite a very low overall survival, patients who received either chemotherapy, radiotherapy or surgery showed a better survival compared with those who did not receive any treatment. Hence, it is essential to improve the survival of patients with esophageal cancer through early detection and timely initiation of the available treatment options.
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