ArticleAnnals of medicine and surgery (2012)2021
Role and value of inflammatory markers in brain tumors: A case controlled study.
Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Article
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- Purines and purinergic receptors in primary tumors of the central nervous system.Purinergic signalling · 2025Article
- Laboratory Markers of Impaired Erythropoiesis in Early Diagnosis of Perioperative Anemias.Sovremennye tekhnologii v meditsine · 2025Observational
- Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function.CNS & neurological disorders drug targets · 2025Article
- Role of inflammatory markers in differentiation and prognostication of gliomas - A prospective cohort study.Surgical neurology international · 2025Article
- Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker for Hospital-Acquired Infections in Neurosurgical Patients.Journal of inflammation research · 2025Article
- Amyloids and brain cancer: molecular linkages and crossovers.Bioscience reports · 2023Review
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
- Plasma nanoDSF Denaturation Profile at Baseline Is Predictive of Glioblastoma EGFR Status.Cancers · 2023Article
- Characterization of structural and functional network organization after focal prefrontal lesions in humans in proof of principle study.Brain structure & function · 2022Article
- Correlation of reduced temporal muscle thickness and systemic muscle loss in newly diagnosed glioblastoma patients.Journal of neuro-oncology · 2022Article
- Is Caperatic Acid the Only Compound Responsible for Activity of LichenAntioxidants (Basel, Switzerland) · 2022Article
- Multiple Faces of the Glioblastoma Microenvironment.International journal of molecular sciences · 2022Review
- Novel molecular panel for evaluating systemic inflammation and survival in therapy naïve glioma patients.World journal of clinical oncology · 2021Article
- Future Biomarkers for Infection and Inflammation in Febrile Children.Frontiers in immunology · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBrain tumor is one of the most devastating diseases in the world. The Pathogenesis is vary in multiple aspect of mechanism. The tumor microenvironment contains many different noncancerous cell types in addition to cancer cells. Inflammation is thought to be one of the factors that influence the oncogenesis process in brain tumors.
methodsThis study is a case controlled analytical study that analyzes the relationship between levels of inflammatory markers with the type of brain tumor. Samples of 35 people were then categorized according to the variables above and analyzing to measure its significance.
resultsBased on demografic study, most sample was male with age was 41-50 years It was found that high levels of procalcitonin were found in the case of glioma brain tumors. Procalcitonin level was considered a significant marker in predicting the severity of a brain tumor (p < 0.005). There was no significant value between the C-Reactive Protein and Neutrophyl-Lymphocyte ratio values for brain tumors. DISCUSSION: Abnormal inflammation is a characteristic of malignant cancers and malignant transformation of low-grade gliomas and other brain tumor. Inflammation-induced activation of transcription factors contributes to the survival and rapid growth of glioma cells.
conclusionAs in other malignant cancers, inflammation may contribute to tumor progression. Biomarkers based on inflammation, such as the classical example of Procalcitonin and C-reactive protein, have been used to assess prognosis of glioma patients. These results should be validated and extended in larger clinical studies.
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