Evidence map›Paper›PMID 33658889›Full record

ArticleCentral-European journal of immunology2020

The analysis of Treg lymphocyte blood percentage changes in patients with head and neck cancer during combined oncological treatment: a preliminary report.

Magdalena Dutsch-Wicherek, Katarzyna Chaberek, Adrianna Makarewicz, Ierant Antoni S, Jacek Witwicki, Ireneusz Bielecki, Łukasz Wicherek

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Central-European journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Magdalena Dutsch-WicherekCenter of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Katarzyna Chabereknd Department of Obstetrics and Gynaecology, Center of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Adrianna Makarewicznd Department of Obstetrics and Gynaecology, Center of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Ierant Antoni Snd Department of Obstetrics and Gynaecology, Center of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Jacek Witwickind Department of Obstetrics and Gynaecology, Center of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Ireneusz BieleckiDepartment of Pediatric Otolaryngology, Head and Neck Surgery, Department of Paediatric Surgery, Medical University of Silesia, Katowice, Poland.
Łukasz Wichereknd Department of Obstetrics and Gynaecology, Center of Postgraduate Medical Education (CMKP), Warsaw, Poland.
Jagiellonian University · PLPostgraduate School of Molecular Medicine · PLMedical University of Silesia · PLUniversity of Bydgoszcz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn patients with cancer, Treg lymphocytes seem to play an important role in promoting tumour growth. The number of circulating Treg cells has been associated with poor survival among patients suffering from various types of cancers. The aim of the present study was to evaluate the changes in the percentage levels of Treg lymphocytes in the blood samples of patients with head and neck cancer during combined treatment with respect to the stage of the disease and the intensity of the radiation reaction as monitored using the Dische scale. MATERIAL AND

methodsPeripheral blood samples were collected from 20 head and neck cancer patients prior to the combined oncological treatment, during, and then one week after the completion of the therapy.

resultsA statistically significantly higher percentage of CD3

conclusionsThe increase in the percentage of Treg cells correlated with an increase in the intensity of the radiation reaction measured using the Dische scale which indicates the advance of the oral mucositis reaction to RTH. In conclusion, because the role of Treg lymphocytes in cancer patients is complex, it is necessary to monitor the percentages of these cells in patients during combined oncological therapies.

Indexed as

Dische scalehead and neck cancerradiotherapy (RTH)Treg cells

Identifiers

PMID33658889
PMCPMC7882406
OpenAlexW3127526345

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.