Evidence map›Paper›PMID 33658880›Full record

ArticlePatient related outcome measures2021

Psychometric Validation of the EQ-5D-3L in Patients with Nontuberculous Mycobacterial (NTM) Lung Disease Caused by

Anuj Shah, Xinyi Ng, Ruchit Shah, Caitlyn Solem, Ping Wang, Marko Obradovic

Open access · goldAbstract read
In one paragraph

Article in Patient related outcome measures, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anuj ShahPatient Centered Outcomes, Pharmerit - An OPEN Health Company, Bethesda, MD, USA.
Xinyi NgPatient Centered Outcomes, Pharmerit - An OPEN Health Company, Bethesda, MD, USA.ORCID 0000-0002-0736-8276
Ruchit ShahPatient Centered Outcomes, Pharmerit - An OPEN Health Company, Bethesda, MD, USA.ORCID 0000-0002-3553-6142
Caitlyn SolemPatient Centered Outcomes, Pharmerit - An OPEN Health Company, Bethesda, MD, USA.ORCID 0000-0002-4914-8052
Ping WangHealth Economics and Outcomes Research, Insmed Incorporated, Bridgewater Township, NJ, USA.
Marko ObradovicHealth Economics and Outcomes Research, Insmed Germany GmbH, Frankfurt am Main, Germany.
Patient-Centered Outcomes Research Institute · USInsmed (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis analysis evaluated the psychometric properties of the EQ-5D-3L among patients with

methodsData from the Phase III CONVERT trial were analyzed. Study measures including the EQ-5D-3L, St. George's Respiratory Questionnaire (SGRQ), the 6-minute walk test (6MWT), and percent predicted forced expiratory volume in 1 second (ppFEV

resultsThe index score was subject to ceiling effects, with 32.6% of patients reporting perfect health at baseline. ICCs for the index (0.80) and VAS (0.85) scores and weighted kappas for the domains (0.5-0.72) indicated adequate test-retest reliability. Correlations between the index/VAS scores and related domains of the SGRQ and 6MWT were as hypothesized (0.31-0.62), and the mean index/VAS scores were significantly different between the 6MWT and ppFEV

conclusionEQ-5D-3L exhibited evidence of validity and reliability but poor responsiveness to clinically meaningful changes in patients with MAC-LD.

Indexed as

EQ-5DNTM lung diseasepsychometric validationreliabilityresponsivenessvalidity

Identifiers

PMID33658880
PMCPMC7920600
OpenAlexW3131543380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.