Evidence map›Paper›PMID 33658822›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Use of Systemic Medications for Treating Adult Atopic Dermatitis in France: Results of a Practice Survey.

Anne-Claire Fougerousse, Caroline Jacobzone, Laure Mery-Bossard, Ziad Reguiai, Catherine Droitcourt, Charles Taieb, François Maccari, GEM ResoEczema Group

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Is there still a place for methotrexate in severe psoriatic arthritis?Therapeutic advances in musculoskeletal disease · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Anne-Claire FougerousseDermatology Department, Hôpital d'Instruction des Armées Bégin, Saint Mandé, Val de Marne, France.ORCID 0000-0002-2850-867X
Caroline JacobzoneDermatology Department, Hôpital du Scroff, Groupe Hospitalier Bretagne Sud, Lorient, Morbihan, France.
Laure Mery-BossardDermatology Department, Centre Hospitalier Intercommunal Poissy Saint Germain en Laye, Saint-Germain-en-Laye, Yvelines, France.
Ziad ReguiaiDermatology Department, Polyclinique Courlancy, Reims, Marne, France.
Catherine DroitcourtDermatology Department, Centre Hospitalier Universitaire, Rennes, Ille et Vilaine, France.
Charles TaiebEmma Clinic, Fontenay-sous-Bois, Val de Marne, France.ORCID 0000-0002-5142-2479
François MaccariPrivate Practice, Saint-Maur-des-Fossés, Val de Marne, France.
GEM ResoEczema Group
Centre Hospitalier de Bretagne Sud · FRCentre Hospitalier Intercommunal de Poissy · FRCentre Hospitalier Universitaire de Rennes · FRHôpital d'Instruction des Armées Bégin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent studies have illustrated that systemic medications are underused for treating adult atopic dermatitis (AD) and that dermatologists have concerns regarding the safety profile of cyclosporine in AD. PATIENTS AND

methodsWe performed a national online practice survey between March and April 2020.

resultsA total of 305 dermatologists responded, 57% with hospital-based activity and 43% with private practice. Overall, 46.9% prescribed cyclosporine for adult AD. Before initiating treatment, 56.9% did not perform evaluation scoring. Reasons for not prescribing cyclosporine were no eligible patients (24.7%), lack of information (52.6%), need for hospital prescription (31.2%), and lack of experience (79.2%). Fifty-four percent of the dermatologists prescribed methotrexate for adult AD. Before initiating treatment, 50.5% did not perform evaluation scoring. Reasons for not prescribing methotrexate were no eligible patients (46.7%), lack of information (39.3%), lack of experience (25.2%), and not approved for AD (47.4%). A total of 2.1% dermatologists prescribed other systemic treatments for adult AD, 9.8% prescribed corticosteroids and 56.4% prescribed dupilumab.

conclusionSystemic treatments for AD are used by half of dermatologists, although cyclosporine and dupilumab must be initiated in hospitals in France. Methotrexate is more frequently used than cyclosporine, although it is not approved for this indication in France. A vast majority of dermatologists do not perform any evaluation scoring before initiating systemic treatment for adult AD.

Indexed as

atopic dermatitiscyclosporinemethotrexatepractice survey

Identifiers

PMID33658822
PMCPMC7920512
OpenAlexW3132416607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.