Evidence map›Paper›PMID 33658812›Full record

ArticleInfection and drug resistance2021

Developing Machine-Learning Prediction Algorithm for Bacteremia in Admitted Patients.

Ebrahim Mahmoud, Mohammed Al Dhoayan, Mohammad Bosaeed, Sameera Al Johani, Yaseen M Arabi

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

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  11. [New predictive models of bacteremia in the emergency department: a step forward].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  12. Bandemia as an Early Predictive Marker of Bacteremia: A Retrospective Cohort Study.International journal of environmental research and public health · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ebrahim MahmoudDepartment of Infectious Disease, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.ORCID 0000-0002-2381-8927
Mohammed Al DhoayanDepartment of Health Informatics, CPHHI, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Mohammad BosaeedDepartment of Infectious Disease, Department of Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Sameera Al JohaniCollege of Medicine, King Saud Bin Abdulaziz University For Health Sciences, Riyadh, Saudi Arabia.ORCID 0000-0001-9952-9067
Yaseen M ArabiCollege of Medicine, King Saud Bin Abdulaziz University For Health Sciences, Riyadh, Saudi Arabia.
King Saud bin Abdulaziz University for Health Sciences · SAKing Abdulaziz Medical City · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBloodstream infection among hospitalized patients is associated with serious adverse outcomes. Blood culture is routinely ordered in patients with suspected infections, although 90% of blood cultures do not show any growth of organisms. The evidence regarding the prediction of bacteremia is scarce. PATIENTS AND

methodsA retrospective review of blood cultures requested for a cohort of admitted patients between 2017 and 2019 was undertaken. Several machine-learning models were used to identify the best prediction model. Additionally, univariate and multivariable logistic regression was used to determine the predictive factors for bacteremia.

resultsA total of 36,405 blood cultures of 7157 patients were done. There were 2413 (6.62%) positive blood cultures. The best prediction was by using NN with the high specificity of 88% but low sensitivity. There was a statistical difference in the following factors: longer admission days before the blood culture, presence of a central line, and higher lactic acid-more than 2 mmol/L.

conclusionDespite the low positive rate of blood culture, machine learning could predict positive blood culture with high specificity but minimum sensitivity. Yet, the SIRS score, qSOFA score, and other known factors were not good prognostic factors. Further improvement and training would possibly enhance machine-learning performance.

Indexed as

bacteremiablood culture predictionmachine learningpredictive medicine

Identifiers

PMID33658812
PMCPMC7920583
OpenAlexW3129287770

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.